On 23 January 2020, Drosten, along with other virologists in Europe and Hong Kong, published a workflow of a real-time PCR (RT-PCR) diagnostic test, which was accepted by the World Health Organization (WHO) and which sent test kits to affected regions.
On 17 March 2020, Drosten was appointed to the European Commission's advisory panel on COVID-19, co-chaired by EC President Ursula von der Leyen and ECHSF Stella Kyriakides.
On 23 March 2020, The Guardian described Drosten as "the [German] country's real face of the coronavirus crisis", and also noted that the Süddeutsche Zeitung had described Drosten as "the nation's corona-explainer-in-chief".
He was a counterpart to Lothar Wieler [de], head of the State's Robert Koch Institute in Berlin, in consulting to German federal and state authorities.