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This video presents a definition of asthma. Triad of Events Types Pathogenesis Role of allergens Role of Mast cells, T Cells, and B cells. Role of eosinophils, and neutrophils. Role of IL4, IL5, and other cytokines. Role of various chemokines. Airway Remodeling Clinical Aspects ... https://www.youtube.com/watch?v=oNnuGtxZzgc
In this talk Dr. Mobeen discusses the case fatality rate (CFR) of COVID-19 by SARS-COV-2, and also compares it to the flu's CFR.
Following topics are covered:
Definition of case fatality rate (CFR)
Limitations of the data used
How rapidly is the virus spreading?
Types of the COVID-19 cases
Mortality risk vs. confirmed deaths
COVID-19 stages
Statistics by age, gender, and comorbidities
Comparison of the COVID-19 CFR with flu CFR
...
https://www.youtube.com/watch?v=BGANwTucSdA
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This video is to explain my automated recording setup, and the software I have written to create a "digital camera man"... Can you send a nice cute name for this camera project?!!
...
https://www.youtube.com/watch?v=cwe6CoFtHK8
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A lecture about the disorders due to the Immune complex depositions. Antigen-antibody complexes activate complement that results in inflammatory damage to the nearby tissue. Serum sickness and Arhus reactions are discussed. Diseases discussed are SLE, Rheumatoid Arthritis, Polyarteritis Nodosum, Post-streptococcal GN, Farmer's lungs (hypersensitivity pneumonitis), etc.
...
https://www.youtube.com/watch?v=WoRUX8FOQ04
Montana Law Restricting Vaccine Status Query is in Appellate Court
Montana's law to restrict queries about a patient or staff's vaccine status was permanently banned by the district court. However, this decision is now in 9th circuit court of appeals. Let's quickly review.
I am not a lawyer, this is not a legal advice. Just a review of the reporting.
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Disclaimer:
This video is not intended to provide assessment, diagnosis, treatment, or medical advice; it also does not constitute provision of healthcare services. The content provided in this video is for informational and educational purposes only.
Please consult with a physician or healthcare professional regarding any medical or mental health related diagnosis or treatment. No information in this video should ever be considered as a substitute for advice from a healthcare professional.
URL list from Sunday, Jan. 21 2024
HB0702.pdf
https://leg.mt.gov/bills/2021/billpdf/HB0702.pdf
COVID-19: Employment Law and Developments Tracker | Practical Law
https://content.next.westlaw.com/practical-law/document/I6c41215f69d111eaadfea82903531a62/COVID-19-Employment-Law-and-Developments-Tracker?viewType=FullText&transitionType=Default&contextData=(sc.Default)
Federal judge strikes down Montana vaccine choice law in health care settings
https://montanafreepress.org/2022/12/09/federal-judge-strikes-down-montana-vaccine-choice-law-in-health-care-settings/
Montana only state to ban vaccine requirements for employees | AP News
https://apnews.com/article/business-health-coronavirus-pandemic-montana-8c47ca9308494b678f41f41764094800
Court stops law that barred vaccine status queries—for all vaccines | American Medical Association
https://www.ama-assn.org/delivering-care/public-health/court-stops-law-barred-vaccine-status-queries-all-vaccines
Montana vaccine law would put physicians in ethical bind | American Medical Association
https://www.ama-assn.org/delivering-care/public-health/montana-vaccine-law-would-put-physicians-ethical-bind
...
https://www.youtube.com/watch?v=3vtwFkry-Og
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...
https://www.youtube.com/watch?v=tRngPDGge-U
Vaccine induced clotting. UK Death Rate. Pakistan.
Let's talk about the situation in Pakistan. UK Death Rate. And, How vaccine induced clotting is not reported after age restriction.
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Pakistan:
Pakistan starts vaccination for 15 to 18. Only Pfizer vaccine will be given to them.
Ivermectin is difficult to find in Pakistan now.
Delta in vaccinated is causing mostly upper respiratory tract infection. Oxygen saturation drop is less observed. However, reinfections in vaccinated are common.
Case discussions for a 74 year old, a 52 years diabetic, a 24 years old female doctor, and a 24 years old male doctor and his friends.
Britain
AstrZeneca and Blood Clotting
Age restriction on AstraZeneca ends report of clotting in the UK
https://www.reuters.com/business/healthcare-pharmaceuticals/age-restrictions-astrazeneca-shot-have-ended-reports-rare-clots-uk-scientists-2021-08-11/
Is there really high death rate among vaccinated in the UK report?
Trial site has an opinion piece that the death rate is higher in the vaccinated than the unvaccinated. Let's review.
https://trialsitenews.com/high-death-rate-among-vaccinated-brings-vaccine-dystopia-into-view/
Based on this report
https://assets.publishing.service.gov.uk/government/uploads/system/uploads/attachment_data/file/1009243/Technical_Briefing_20.pdf
The correct way to look at the data
https://www.ons.gov.uk/peoplepopulationandcommunity/healthandsocialcare/conditionsanddiseases/articles/coronaviruscovid19latestinsights/vaccines
Disclaimer:
This video is not intended to provide assessment, diagnosis, treatment, or medical advice; it also does not constitute provision of healthcare services. The content provided in this video is for informational and educational purposes only.
Please consult with a physician or healthcare professional regarding any medical or mental health related diagnosis or treatment. No information in this video should ever be considered as a substitute for advice from a healthcare professional.
...
https://www.youtube.com/watch?v=ao7DVnrDV2M
Allergic Reactions to Pfizer/BionTech Vaccine in UK
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Two healthcare workers in UK have experienced anaphylactoid reactions from the Pfizer COVID vaccine. Anaphylactoid reaction can have rashes, difficulty in breathing, and drop in blood pressure. An anaphylactoid reaction is different from an anaphylaxis reaction which can be life-threatening. Both healthcare workers are recovering well.
A notable point is that both healthcare workers who developed the allergic reaction were severely allergic to other substances as well and carried adrenaline injections with them.
MHRA has advised against administering the Pfizer vaccine to anyone that has similar allergic reaction history.
Despite the allergies the vaccination program continues to roll out in UK.
Anaphylaxis
https://en.wikipedia.org/wiki/Anaphylaxis
Basophils
https://en.wikipedia.org/wiki/Basophil
Mast cells
https://en.wikipedia.org/wiki/Mast_cell
Pfizer vaccine side-effects
https://news.yahoo.com/just-got-best-look-yet-140514936.html
FDA briefing about the Pfizer vaccine side effects.
https://www.fda.gov/media/144245/download
FDA says that the Pfizer vaccine is safe and effective
https://news.yahoo.com/fda-says-pfizer-vaccine-safe-150356697.html
Allergy warning by MHRA
https://www.bbc.com/news/health-55244122
A great explainer for the vaccine allergic reactions
https://www.nbc29.com/2020/12/09/explainer-allergic-reactions-vaccines-rare-short-lived/
Canada and Bahrain also approve Pfizer/BionTech’s vaccine
https://globalnews.ca/news/7474273/pfizer-emergency-use-coronavirus-vaccine-canada/
UAE approves SinoPharm's vaccine
https://www.khaleejtimes.com/coronavirus-pandemic/uae-vaccine-for-coronavirus-sinopharms-jab-approved
#koolbeens #drbeen #COVID
...
https://www.youtube.com/watch?v=BS39cLCoom0
FDA Authorizes Pfizer for 6mo to Under 5, and Moderna COVID Vaccines for 6mo to 17
I am comfortable (somewhat with Moderna), but Pfizer authorization does not seem correct to me. Let's review the authorization data once more. Having said that, Novavax is still in review because of their change to the manufacturing process.
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Disclaimer:
This video is not intended to provide assessment, diagnosis, treatment, or medical advice; it also does not constitute provision of healthcare services. The content provided in this video is for informational and educational purposes only.
Please consult with a physician or healthcare professional regarding any medical or mental health related diagnosis or treatment. No information in this video should ever be considered as a substitute for advice from a healthcare professional.
URL list from Friday, Jun. 17 2022
Coronavirus (COVID-19) Update: FDA Authorizes Moderna and Pfizer-BioNTech COVID-19 Vaccines for Children Down to 6 Months of Age | FDA
https://www.fda.gov/news-events/press-announcements/coronavirus-covid-19-update-fda-authorizes-moderna-and-pfizer-biontech-covid-19-vaccines-children
Vaccines and Related Biological Products Advisory Committee June 14-15, 2022 Meeting Announcement - 06/14/2022 | FDA
https://www.fda.gov/advisory-committees/advisory-committee-calendar/vaccines-and-related-biological-products-advisory-committee-june-14-15-2022-meeting-announcement
Vaccines and Related Biological Products Advisory Committee June 15, 2022 Meeting Presentation- COVID19- FDA Review of Effectiveness and Safety of Moderna Vaccines in 6mo to 5yr
https://www.fda.gov/media/159254/download
Vaccines and Related Biological Products Advisory Committee June 15, 2022 Meeting Presentation- Sponsor- Pfizer COVID19 Vaccine for 6mo-4yr
https://www.fda.gov/media/159258/download
Vaccines and Related Biological Products Advisory Committee June 15, 2022 Meeting Presentation- COVID19- FDA Review of Effectiveness and Safety of Pfizer Vaccines in 6mo to 4yr
https://www.fda.gov/media/159255/download
Vaccines and Related Biological Products Advisory Committee June 15, 2022 Meeting Presentation- Sponsor- Moderna COVID19 Vaccine for 6mo-5yr
https://www.fda.gov/media/159257/download
Novavax COVID-19 Vaccine: FDA EAU Approval Likely Delayed
https://www.healthline.com/health-news/fda-approval-of-the-novavax-covid-19-vaccine-delayed-by-manufacturing-changes
...
https://www.youtube.com/watch?v=GEW-qjQSN9c
Revealed - How SARS-COV-2 Escapes Our Immune System
This thorough study reveals the mechanism of immune escape by SARS-COV-2. Let's review.
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Want to support this work?:
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Disclaimer:
This video is not intended to provide assessment, diagnosis, treatment, or medical advice; it also does not constitute provision of healthcare services. The content provided in this video is for informational and educational purposes only.
Please consult with a physician or healthcare professional regarding any medical or mental health related diagnosis or treatment. No information in this video should ever be considered as a substitute for advice from a healthcare professional.
URL list from Tuesday, Aug. 2 2022
SARS-CoV-2 inhibits induction of the MHC class I pathway by targeting the STAT1-IRF1-NLRC5 axis | Nature Communications
https://www.nature.com/articles/s41467-021-26910-8
NLRC5: a newly discovered MHC class I transactivator (CITA) - PMC
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3323719/
CD45 functions as a signaling gatekeeper in T cells | Science Signaling
https://www.science.org/doi/10.1126/scisignal.aaw8151#:~:text=CD45%20is%20a%20receptor%2Dtype,to%20phosphorylate%20the%20TCR%20complex.
Transactivation - Wikipedia
https://en.wikipedia.org/wiki/Transactivation
Promoter
https://www.genome.gov/genetics-glossary/Promoter
Epigenetic Regulation and Measurement of Epigenetic Changes - PMC
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5839622/#:~:text=Epigenetic%20regulation%20increases%20the%20functional%20complexity%20of%20DNA%20by%20providing,epigenetic%20modulation%20of%20gene%20expression.
T Cells and MHC Proteins - Molecular Biology of the Cell - NCBI Bookshelf
https://www.ncbi.nlm.nih.gov/books/NBK26926/#:~:text=Class%20I%20MHC%20proteins%20are,microbe%20such%20as%20a%20virus.
Transcription factor - Wikipedia
https://en.wikipedia.org/wiki/Transcription_factor
Interferon gamma - Wikipedia
https://en.wikipedia.org/wiki/Interferon_gamma
Interferon-γ signaling. Canonical IFN-γ signaling pathway requires... | Download Scientific Diagram
https://www.researchgate.net/figure/Interferon-g-signaling-Canonical-IFN-g-signaling-pathway-requires-activation-of-its_fig1_345005034
Interferon regulatory factor 1 (IRF1) and anti-pathogen innate immune responses - PMC
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7819612/
...
https://www.youtube.com/watch?v=Qb3KWMTjW-k