Author: Sam Thiagalingam File Type: pdf With over 200 types of cancer diagnosed to date, researchers the world over have been forced to rapidly update their understanding of the biology of cancer. In fact, only the study of the basic cellular processes, and how these are altered in cancer cells, can ultimately provide a background for rational therapies. Bringing together the state-of-the-art contributions of international experts, Systems Biology of Cancer proposes an ultimate research goal for the whole scientific community exploiting systems biology to generate in-depth knowledge based on blueprints that are unique to each type of cancer. Readers are provided with a realistic view of what is known and what is yet to be uncovered on the aberrations in the fundamental biological processes, deregulation of major signaling networks, alterations in major cancers and the strategies for using the scientific knowledge for effective diagnosis, prognosis and drug discovery to improve public health.**
Author: Kathryn J. Norlock
File Type: pdf
The feeling that one cant get over a moral wrong is challenging even in the best of circumstances. This volume considers challenges to forgiveness in the most difficult circumstances. It explores forgiveness in criminal justice contexts, under oppression, after genocide, when the victim is dead or when bystanders disagree, when many different negative reactions abound, and when anger and resentment seem preferable and important. The book gathers together a diverse assembly of authors with publication and expertise in forgiveness, while centering the work of new voices in the field and pursuing new lines of inquiry grounded in empirical literature. Some scholars consider how forgiveness influences and is influenced by our other mental states and emotions, while other authors explore the moral value of the emotions attendant upon forgiveness in particularly challenging contexts. Some authors critically assess and advance applications of the standard view of forgiveness predominant in Anglophone philosophy of forgiveness as the overcoming of resentment, while others offer rejections of basic aspects of the standard view, such as what sorts of feelings are compatible with forgiving. The book offers new directions for inquiry into forgiveness, and shows that the moral psychology of forgiveness continues to enjoy challenges to its theoretical structure and its practical possibilities.
Author: Edd Morris
File Type: epub
A guide to some of the most historical and picturesque castles in England for romantics and Anglophiles alike. Castles have shaped England. For almost one thousand years, castles have been the settings of siege and battle, dens of plotting and intrigue, and refuges for troubled kings. Today, the romantic yet ruinous shapes of once grand fortresses stud the English countrysidea reminder of turbulent times past. Exploring English Castles provides readers with a breathtaking tour through the grandest castles of England. It brings ruins to life through true stories of royalty, chivalry, deception, and intrigue, played out within formerly majestic walls. Uncover the secret of Bodiam Castle, Sussexa fortress seemingly from a fairy tale, built for a knight returning from the Hundred Years War. Discover how Mary Tudor, first queen of England, took refuge in Framlingham Castle, Suffolk, overturning a wily plot to deny her the throne. Unearth a delicate love story between Queen Elizabeth I and Robert Dudley, which unfolds against the genteel backdrop of Kenilworth Castle, Warwickshire. Filled with evocative photographs, awe-inspiring historical tales, and gentle humor, Exploring English Castles will delight any armchair historian, travel aficionado, or fan of historical fiction. **
Author: Andrew Cooper
File Type: pdf
Reframes philosophical understanding of, and engagement with, tragedy. In The Tragedy of Philosophy Andrew Cooper challenges the prevailing idea of the death of tragedy, arguing that this assumption reflects a problematic view of both tragedy and philosophyone that stifles the profound contribution that tragedy could provide to philosophy today. To build this case, Cooper presents a novel reading of Immanuel Kants Critique of Judgment. Although this text is normally understood as the final attempt to seal philosophy from the threat of tragedy, Cooper argues that Kants project is rather a creative engagement with a tragedy that is specific to philosophy, namely, the inevitable failure of attempts to master nature through knowledge. Kants encounter with the tragedy of philosophy turns philosophys gaze from an exclusive focus on knowledge to matters of living well in a world that does not bend itself to our desires. Tracing the impact of Kants Critique of Judgment on some of the most famous theories of tragedy, including those of G. W. F. Hegel, Friedrich Nietzsche, Martin Heidegger, and Cornelius Castoriadis, Cooper demonstrates how these philosophers extend the project found in both Kant and the Greek tragedies the attempt to grasp nature as a domain hospitable to human life.
Author: Edward O. Wilson
File Type: epub
Review bWorld Literature Todaybb Editors PickbEnchanting. . . . The Poetic Species is a wonderful read in its entirety, short yet infinitely simulating. bBrain PickingsbThe principle of consilience, or the unity of knowledge, infuses this conversation between biologist E. O. Wilson and poet Robert Hass. . . . The eminent duo explore echoes and parallels in their respective fields with eloquent concision, from Wilsons advice to poets (Colonize science) to Hasss musings on the interplay of selfish gene and social imperative in imagination. bNature International Weekly Journal of SciencebThe Poetic Species explores the intersection of science and the arts in relation to the staggering environmental crisis the world is encountering. I am encouraged by this call to action by both scientific and literary communities and curious about the possible responses. bWorld Literature Todaybb Editors Pick citationbEvery page offers something worth contemplating . . . The Poetic Species is a fascinating foray into the ways were connected to each other and the natural worldhighly recommended reading. bRosemary & Reading Glassesb About the Author bEdward O. Wilsonb is an American biologist, researcher, theorist, naturalist, and author who is often dubbed the father of sociobiology. His biological specialty is myrmecology, the study of ants, on which he is considered to be the worlds leading authority. Wilson is the author of the New York Times bestsellers The Social Conquest of Earth and Anthill A Novel, as well as the Pulitzer Prizewinning On Human Nature and (with Bert Holldobler) The Ants. For his contributions in science and conservation, he has received more than 100 awards from around the world. A professor emeritus at Harvard University, he lives in Lexington, Massachusetts.bRobert Hassb work is rooted in the landscapes of his native northern California. In his tenure as U. S. Poet Laureate, Robert Hass spent two years battling American illiteracy armed with the mantra imagination makes communities. For Hass, everything is connected. When he works to heighten literacy, he is also working to promote awareness about the environment. Hass has published many books of poetry including Field Guide, Praise, Human Wishes and Sun Under Wood, as well as a book of essays on poetry, Twentieth Century Pleasures. Time and Materials, his 2007 poetry collection, won both the Pulitzer Prize and the National Book Award. His most recent volume of poetry is The Apple Trees at Olema New and Selected Poems. He recently published a book of essays titled What Light Can Do Essays on Art, Imagination, and the Natural World. Awarded the MacArthur Genius Fellowship, the National Book Critics Circle Award twice (in 1984 and 1997), and the Yale Series of Younger Poets in 1973, Hass is a professor of English at University of California-Berkeley.Foreword contributor bLee Briccettib was born in Italy and raised in the United States. She currently lives in New York City where she has been the long-time executive director of Poets House, a national poetry archive and literary center. She has received fellowships from the New York Foundation for the Arts and the Fine Arts Work Center in Provincetown. Her book of poetry, Day Mark, was published in 2005 by Four Way Books.
Author: Mary Jane Jacob
File Type: pdf
John Dewey is known as a pragmatic philosopher and progressive architect of American educational reform, but some of his most important contributions came in his thinking about art.Dewey argued that there is strong social value to be found in art, and it is artists who often most challenge our preconceived notions. Dewey for Artists shows us how Dewey advocated for an art of democracy. Identifying the audience as co-creator of a work of art by virtue of their experience, he made space for public participation. Moreover, he believed that societies only becomeand remaintruly democratic if its citizens embrace democracy itself as a creative act, and in this he advocatedfor the social participation of artists.Throughout the book, Mary Jane Jacob draws on the experiences of contemporary artists who have modeled Deweys principles within their practices. We see how their work springs from deeply held values. We see, too, how carefully considered curatorial practice can address the manifold ways in which aesthetic experience happens and, thus, enable viewers to find greater meaning and purpose. And it is this potential of art for self and social realization, Jacob helps us understand, that further ensures Deweys legacyand the culture we live in.
Author: E. Dawson Varughese
File Type: pdf
This book investigates the intersection of Indian society, the encoding of post-millennial modernity and ways of seeing through the medium of Indian graphic narratives. If seeing in Indian cultures is a mode of knowing then what might we decode and know from the Indian graphic narratives examined here? The book posits that the seeing of post-millennial Indian graphic narratives revolves around a visuality of the inauspicious, complemented by narratives of the same. Examining both form and content across nine Indian, post-millennial graphic narratives, this book will appeal to those working in South Asian visual studies, cultural studies and comics-graphic novel studies more broadly.**From the Back CoverE. Dawson Varugheses in-depth readings of the form and content of lesser known narratives that powerfully enrich the range and scope of alternative comics foreground the importance of a corpus that tackles all basic issues of post-millennial modernity in India.Jan Baetens, co-author with Hugo Frey of The Graphic NovelThe old and the new are brought together in interesting ways in her understanding of post-millennial Indian identities through the graphic novel and other visual cultural forms. Varughese offers us a compelling read and invaluable insights. Rajinder Dudrah, Birmingham City University, UKThis book investigates the intersection of Indian society, the encoding of post-millennial modernity and ways of seeing through the medium of Indian graphic narratives. If seeing in Indian cultures is a mode of knowing then what might we decode and know from the Indian graphic narratives examined here? The book posits that the seeing of post-millennial Indian graphic narratives revolves around a visuality of the inauspicious, complemented by narratives of the same. Examining both form and content across nine Indian, post-millennial graphic narratives, this book will appeal to those working in South Asian visual studies, cultural studies and comics-graphic novel studies more broadly.E. Dawson Varughese is an independent, global cultural studies scholar, specialising in post-millennial Indian visual and literary cultures. She publishes on genre fiction, book cover design and public wall art. Her latest book is Genre Fiction of New India (Routledge, 2016). She was a Visiting Fellow at the University of Delhi in 2017. www.beyondthepostcolonial.comAbout the Author E. Dawson Varughese is an independent, global cultural studies scholar, specialising in post-millennial Indian visual and literary cultures. She publishes on genre fiction, book cover design and public wall art. Her latest book is Genre Fiction of New India (Routledge, 2016). She was a Visiting Fellow at the University of Delhi in 2017. www.beyondthepostcolonial.com
Author: Wilson Jeremiah Moses
File Type: pdf
Afrocentrism and its history have long been disputed and controversial. In this important book, Wilson Moses presents a critical and nuanced view of the issues. Tracing the origins of Afrocentrism since the eighteenth century, he examines the combination of various popular mythologies, some of them mystical and sentimental, others perfectly reasonable. A level presentation in what is often a shouting match, Afrotopia is a rich history of black intellectual life and the concept of race. **
Author: Gordon Ramsay
File Type: epub
Everyone thinks they know the real Gordon Ramsay rude, loud, driven, stubborn. But this is his real story... In this fast-paced, bite-sized edition of his bestselling autobiography Ramsay tells the real story of how he became the worlds most famous and infamous chef his difficult childhood, his brothers heroin addiction, his failed first career as a footballer, his fanatical pursuit of gastronomic perfection and his TV persona - all the things that have made him the celebrated culinary talent and media powerhouse that he is today. Gordon talks frankly about his tough childhood his fathers alcoholism and violence and the effects on his relationships with his mother and siblings his first career as a footballer how the whole family moved to Scotland when he was signed by Glasgow Rangers at the age of fifteen, and how he coped when his career was over due to injury just three years later his brothers heroin addiction. Gordons early career learning his trade in Paris and London how his career developed from there his time in Paris under Albert Roux and his seven Michelin-starred restaurants. kitchen life Gordon spills the beans about life behind the kitchen door, and how a restaurant kitchen is run in Anthony Bourdain-style. and how he copes with the impact of fame on himself and his family his television career, the rapacious tabloids, and his own drive for success.