These boots are made for walkin
And that's just what they'll do
One of these days, these boots are gonna walk all over you
Yeah.. ???
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https://www.youtube.com/watch?v=DvHrexRZOBs
"The Telegraph"
Neanderthal gene probably caused up to a million Covid deaths
A single Neanderthal gene found in one in six Britons is likely to blame for up to a million Covid deaths, according to an Oxford academic.
The LZTFL1 gene is a Neanderthal gene found on chromosome three and has been previously shown to double a person’s risk of severe disease and death.
But before now there had never been an estimated figure for how many lives were lost to this single piece of genetic code.
Roughly 15 per cent of Europeans have the Neanderthal form of the gene, compared to about 60 per cent of South Asians.
Dr James Davies of the University of Oxford, a genomic expert and ICU doctor who worked on the Covid wards during the pandemic, discovered the innocuous gene’s lethal role last year after creating a brand new cutting-edge way of looking at DNA in exceptional detail.
The method allowed him to identify LZTFL1 as the culpable gene increasing mortality, whereas previous methods had failed to narrow it down beyond 28 different genes.
Speaking at the Cheltenham Science Festival, Dr Davies said: “We used the technique and it identified a virtually understudied gene called LZTFL1 and at the time that this had not been linked to infection at all.
“It’s a single letter difference out of three billion. This tiny section of DNA doubles your risk of dying from Covid.
“It's position 45,818,159 on chromosome three, and it's a single change. If you've got a G at that site, it's low risk. And if you have an A at that site it is high risk.”
His team believe that the Neanderthal gene changes how a cell behaves when the SARS-CoV-2 virus binds to the ACE2 receptor on a human cell.
In most people, this leads to the cell then changing shape and becoming less specialised and less prone to infection, stymying the progression of the infection.
“What this high risk variant does is it creates a new signal that tells that gene to stay on for slightly too long in response to infection,” Prof Davies said.
“And so they stay in this state where they're highly specialised, and they're prone to infection for longer.”
The number of deaths globally from this nefarious genetic variant “is in the hundreds of thousands to a million,” he told the audience.
'Dinner date' between human and Neanderthal
Dr Davies and his colleague from Oxford Brookes University, Dr Simon Underdown, a biological anthropologist, also revealed that the Neanderthal gene first infiltrated humans 60,000 years ago after one romantic liaison and interspecies tryst between a human and a neanderthal. A solitary coupling event across species lines saw the deadly Covid gene jump from our now-extinct cousin species into us.
“If this dinner date between the human and the Neanderthal had gone wrong, we would have had a much better time in Covid, we would have had hundreds of thousands less deaths,” said Prof Davies.
“The reason that we know that is that it's inherited as this block with 28 single letter changes, and you can track that all the way back and it has to be a single event. It's just so unlikely that you get all 28 changes at the same time and in the same block.”
Neanderthals 'looked just like us'
Dr Underwood added that Neanderthals would likely have looked very similar to humans.
“Arguably, they look just like us,” he said. “If you dress one of these guys up in a hat and a coat…you wouldn't give them a second glance.
“What would happen when a Neanderthal came into contact with Homo sapiens? Would they even recognise them as different? I would argue very much that they wouldn't.”
“They would have thought they were unusual insofar as they didn't look exactly alike but they were similar enough that they probably wouldn't have even known it was something that different.
“We see Neanderthal integration, or sex, taking place around 60,000 years ago after they left Africa and this is the event where James's gene jumps across.
“This is the event where the gene that gives you more severe Covid jumps across into the Homo sapien lineage.”
In January, scientists announced Earth’s magnetic field was moving quickly and in an unexpected way—traveling from Canada towards Siberia faster than it should have—and no one knew exactly why.
The sudden change in the position of the magnetic north pole meant scientists at NOAA had to do an unscheduled update to the World Magnetic Map model—the system used across the globe to ensure the accuracy of positioning in systems like GPS and aircraft navigation.
The magnetic north pole is always on the move, but the shift of its position is generally quite steady. The unexpected change could be related to a strange phenomenon known as “geomagnetic jerks.” First discovered in 1978, these jerks are characterised by the magnetic field abruptly and unexpectedly accelerating at fairly random intervals.
In a study published in the journal Nature Geology, researchers have now found the cause of geomagnetic jerks, solving the 40 year mystery.
Earth’s magnetic field is produced by the planet’s metallic core. Movements within the core cause variations to the field. This could be slow convection over long time scales, or “rapid” hydromagnetic waves that can be seen over just a few years. The geomagnetic jerks are thought to result from the second type of movement.
Julien Aubert from France’s CNRS, and colleagues used supercomputers to create a model for the jerks. They recreated conditions thought to exist at Earth’s core and then let the computer carry out what would be four million hours of calculations. From this, scientists were able to reproduce the conditions that take place before a geomagnetic jerk.
Findings showed the jerks arise when hydromagnetic waves are emitted in the inner core. The waves are amplified as they rise to the surface of the core, creating disturbances that fit with what we observe during geomagnetic jerks.
“The origin of jerks has been a riddle for geophysicists since their discovery 40 years ago,” Aubert told Newsweek. “On theoretical, or more observational grounds, many mechanisms have been proposed during those years, involving other types of core motions or waves. In our opinion the strength of our proposal is that it relies on self-consistent computer simulations of the geodynamo i.e. it solves the equations for motion and magnetic field generation that derive from the first principles of physics. So geomagnetic jerks are self-consistently generated in a framework requiring a minimal number of prior assumptions.”
He said that one limitation of the paper is that their model does not necessarily fit with geomagnetic jerks recorded in earlier periods, like the one that took place in 1969, for example.
The current findings are part of a longer-term project where scientists hope to predict the evolution of th
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https://www.youtube.com/watch?v=MQFvuKNBWyw
The fourth Long March-5 rocket, to be used to launch China's first Mars exploration mission, was vertically transported to the launching area at the Wenchang Space Launch Centre in south China's Hainan Province on Friday. The carrier rocket, coded as Long March-5 Y4, is planned to be launched in late July or early August, according to the China National Space Administration.
The China National Space Agency (CNSA) will be launching their first interplanetary mission to Mars on top of their heavy lift rocket, the Long March 5! This will be the heaviest payload ever sent to Mars and features orbiters, a lander and a rover!!!
China's Mars rover will likely attempt to land at a site in north-eastern Mars, according to a new paper published just days ahead of the mission's launch.
China’s heaviest rocket has rolled to its launch pad for lift-off Thursday with the country’s first Mars landing mission, an ambitious attempt to place an orbiter around the Red Planet and a robotic rover on the Martian surface in early 2021.
The Chinese mission, named Tianwen 1, is the second of three probes taking aim on the Red Planet this month, when Mars is properly positioned in its orbit around the sun to allow a direct journey from Earth. Such launch opportunities only come about once every 26 months.
A Long March 5 rocket is set for liftoff with China’s Tianwen 1 mission some time between 12 a.m. and 3 a.m. EDT (0400-0700 GMT) Thursday, according to public notices warning ships to steer clear of downrange drop zones along the launcher’s flight path.
The launch will be the first operational flight of China’s Long March 5 rocket, the most powerful launch vehicle in the country’s inventory. Ground crews at the Wenchang Space Launch Center on Hainan Island — China’s newest launch site — transferred the Long March 5 rocket to its launching stand Friday for final pre-flight checkouts.
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https://www.youtube.com/watch?v=2v3qykwteuU