**✪✪✪✪✪ http://www.theaudiopedia.com ✪✪✪✪✪**

What does DISPOSITION INDEX mean? DISPOSITION INDEX meaning - DISPOSITION INDEX definition - DISPOSITION INDEX explanation. What is the meaning of DISPOSITION INDEX? What is the definition of DISPOSITION INDEX? What does DISPOSITION INDEX stand for? What is DISPOSITION INDEX meaning? What is DISPOSITION INDEX definition?

Source: Wikipedia.org article, adapted under https://creativecommons.org/licenses/by-sa/3.0/ license.

Disposition index (DI) is the product of insulin sensitivity times the amount of insulin secreted in response to blood glucose levels. Insulin resistant individuals can maintain normal responses to blood glucose due to the fact that higher levels of insulin are secreted as long as the beta cells of the pancreas are able to increase their output of insulin to compensate for the insulin resistance. Loss of function of the beta cells, reducing their capacity to compensate for insulin resistance, results in a lower disposition index.

A lowering of disposition index predicts the conversion of insulin resistance to diabetes mellitus type 2. Disposition index, but not insulin resistance, can predict type 2 diabetes in persons with normal blood glucose levels, but who do not have a family history (genetic predisposition) to type 2 diabetes.

Disposition index can be increased by aerobic exercise, but only to the extent that insulin sensitivity is improved.