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Diffuse Large B-Cell Lymphoma Diagnosis& Treatment | Aggressive B-Cell Non-Hodgkin’s Lymphoma
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Hematological malignancies can be divided into leukemias, lymphomas, and multiple myeloma.
Lymphomas can be divided into Hodgkin's lymphoma and non-Hodgkin's lymphoma.
Non-Hodgkin's lymphoma can be subdivided into aggressive lymphoma and indolent lymphoma.
Aggressive non-Hodgkin's lymphomas include:
*Diffuse large B-cell lymphoma (DLBCL)
*Burkitt's lymphoma.
*Mantle cell lymphoma.
*Precursor T-cell lymphoblastic lymphoma.
*B-lymphoblastic lymphoma.
Indolent non-Hodgkin's lymphomas include:
*Follicular lymphoma
*Marginal zone B-cell lymphoma (MALToma)
*Hairy cell leukemia/ lymphoma.
*Waldenstrom macroglobulinemia.
*Mycosis fungoides/ Sezary syndrome.
Diffuse Large B-cell lymphoma (DLBCL) is an aggressive Non-Hodgkin's lymphoma (NHL)...It's the most common NHL.
To diagnose, you need a core needle biopsy or an excisional biopsy of the lymph node
Uric acid levels can be high---Give allopurinol (Xanthine oxidase inhibitor).
Staging of cancer is important (Ann-Arbor classification based on history, physical exam and CT scan)
Treatment: Combination Chemotherapy (R-CHOP) regimen.
Tumor lysis syndrome can ensue.
PET scan is helpful.
The lymph node is a bean-shaped body (not a gland) that interrupts the flow of lymph through the lymphatic vessels.
Afferent lymphatics go towards the lymph node, while efferent exits the node. The lymph node has cortex (which contains the follicle, germinal center, mantle, and margin).
Lymphocyte activation and differentiation occur in the lymph node.
Lymph is a colorless fluid that floats in the lymphatic vessels (lymphatics) of your lymphatic systems.
Formed from the interstitial fluid (extracellular fluid) and returns back to the big veins (Superior vena cava) through the thoracic duct and Right lymphatic duct.
Lymph slows down when it passes in lymph nodes.
Lacteals are a special type of lymph, they are milky because they contain chylomicrons.
Lymph node enlargement can happen in cases of lymphoma (painless lymphadenopathy) or infection (painful).
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https://www.youtube.com/watch?v=yira-lBzWFY
Hematological malignancies can be divided into leukemias, lymphomas, and multiple myeloma.
Lymphomas can be divided into Hodgkin's lymphoma and non-Hodgkin's lymphoma.
Non-Hodgkin's lymphoma can be subdivided into aggressive lymphoma and indolent lymphoma.
Aggressive non-Hodgkin's lymphomas include:
*Diffuse large B-cell lymphoma (DLBCL)
*Burkitt's lymphoma.
*Mantle cell lymphoma.
*Precursor T-cell lymphoblastic lymphoma.
*B-lymphoblastic lymphoma.
Indolent non-Hodgkin's lymphomas include:
*Follicular lymphoma
*Marginal zone B-cell lymphoma (MALToma)
*Hairy cell leukemia/ lymphoma.
*Waldenstrom macroglobulinemia.
*Mycosis fungoides/ Sezary syndrome.
Diffuse Large B-cell lymphoma (DLBCL) is an aggressive Non-Hodgkin's lymphoma (NHL)...It's the most common NHL.
To diagnose, you need a core needle biopsy or an excisional biopsy of the lymph node
Uric acid levels can be high---Give allopurinol (Xanthine oxidase inhibitor).
Staging of cancer is important (Ann-Arbor classification based on history, physical exam and CT scan)
Treatment: Combination Chemotherapy (R-CHOP) regimen.
Tumor lysis syndrome can ensue.
PET scan is helpful.
The lymph node is a bean-shaped body (not a gland) that interrupts the flow of lymph through the lymphatic vessels.
Afferent lymphatics go towards the lymph node, while efferent exits the node. The lymph node has cortex (which contains the follicle, germinal center, mantle, and margin).
Lymphocyte activation and differentiation occur in the lymph node.
Lymph is a colorless fluid that floats in the lymphatic vessels (lymphatics) of your lymphatic systems.
Formed from the interstitial fluid (extracellular fluid) and returns back to the big veins (Superior vena cava) through the thoracic duct and Right lymphatic duct.
Lymph slows down when it passes in lymph nodes.
Lacteals are a special type of lymph, they are milky because they contain chylomicrons.
Lymph node enlargement can happen in cases of lymphoma (painless lymphadenopathy) or infection (painful).
Thanks for watching…
Don't forget to subscribe...and ring the bell to get notified.
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Hemophilia is a genetic Coagulation Disorder characterized by abnormally excessive bleeding ? even after a minor scratch. Hemophilia is divided into three subtypes: hemophilia A, hemophilia B, and hemophilia C. Hemophilia A and hemophilia B are X-linked recessive, whereas hemophilia C is autosomal recessive.'
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Platelet count is one of the lab tests used by a doctor or a hematologist to assess whether your platelet number is normal, low (thrombocytopenia) or high (thrombocytosis).
Bleeding ? time (BT) is another test for platelet function.
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5 ? Minerals in 12 Minutes | Diet & Nutrition | Quick Review. What’s the difference between vitamins and minerals? Vitamins and Minerals are important for a good diet…Vitamins vs Minerals | Diet & Nutrition…Are you deficient in vitamins or minerals? do they help in body’s metabolism? Vitamins (Water-soluble vitamins, and fat-soluble vitamins) | Biochemistry…Vitamin B1 (Thiamine), Vitamin B2 (Riboflavin), Vitamin B3 (Niacin), Vitamin B5 (Pantothenic acid), Vitamin B6 (Pyridoxine), Vitamin B7 (Biotin), Vitamin B9 (Folate, Folic acid), Vitamin B12 (Cobalamin). Fruits, Vegetables, Meet (beef, chicken, seafood), nuts, grains, fibers.
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https://www.youtube.com/watch?v=OBXbW87cgFo
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Created
1 year ago
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video/mp4
English
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VIDEO
VITAM
vitamin-b12-cobalamin-deficiency-causes
??Animated Mnemonics (Picmonic): https://www.picmonic.com/viphookup/medicosis/
- With Picmonic, get your life back by studying less and remembering more. Medical and Nursing students say that Picmonic is the most comprehensive and effective way to bridge learning and test prep...
Disclaimer: I use affiliate links....
►???Antibiotics Lectures: https://www.medicosisperfectionalis.com/products/courses/antibiotics/ ... Check out my brand new "Electrolytes" course at https://www.medicosisperfectionalis.com/products/course/electrolytes/ and use the PROMO code: ELECTROLYTES50 to get a 50% discount. In cases of vitamin B12 deficiency, both Homocysteine and Methylmalonate are elevated.
RDW is elevated in Vitamin B12 deficiency as well as in folate deficiency.
Strict vegans are at risk of developing vitamin B12 deficiency.
To make red blood cells during hematopoiesis, DNA replications require the presence of vitamin B12 and folate.
Folate is stored in your liver for months.
Vitamin B12 is stored in your liver for years.
Vitamin B12 (cobalamin) deficiency = Megaloblastic anemia+ Neurological Symptoms.
Folate deficiency = megaloblastic anemia [withOUT neurological symptoms]
► Get my notes and cases at https://www.patreon.com/medicosis ...
My FAVORITE BOOK to study Pathology and pathophysiology for step 1 USMLE is Goljan, you can check it out here: https://goo.gl/9ojg6M
(Disclaimer: The medical information contained herein is intended for physician medical licensing exam review purposes only, and are not intended for diagnosis of any illness. If you think you may be suffering from any medical condition, you should consult your physician or seek immediate medical attention.)
Disclaimer: these links are affiliate links so that I get paid a percentage of the sale, to support the channel, however, the customer is not affected as they pay the same price.
Click the Subscribe button to get new videos every week.
To watch all my Hematology videos, check out this playlist: https://www.youtube.com/playlist?list=PLYcLrRDaR8_eoNz6dxXolh1XMEietcniU
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The funniest thing is that I have a playlist containing only mnemonics, yes, MEDICAL MNEMONICS, here: https://www.youtube.com/playlist?list=PLYcLrRDaR8_c4yXU3bwjIUNUk7C684ngd
Remember: Cobalamin deficiency is a megaloblastic anemia plus neurological symptoms, whereas folate deficiency is just a megaloblastic anemia. If you like my videos, please consider leaving a tip at https://www.paypal.me/perfectionalis/
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https://www.youtube.com/watch?v=7HqHq6n7rwM
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Created
1 year ago
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video/mp4
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VIDEO
RHEUM
rheumatoid-arthritis-part-8-diagnosis
??Animated Mnemonics (Picmonic): https://www.picmonic.com/viphookup/medicosis/
- With Picmonic, get your life back by studying less and remembering more. Medical and Nursing students say that Picmonic is the most comprehensive and effective way to bridge learning and test prep...
Disclaimer: I use affiliate links....
►???Antibiotics Lectures: https://www.medicosisperfectionalis.com/products/courses/antibiotics/ ... Check out my brand new "Electrolytes" course at https://www.medicosisperfectionalis.com/products/course/electrolytes/ and use the PROMO code: ELECTROLYTES50 to get a 50% discount.
► Visit my website: https://www.medicosisperfectionalis.com/ My Favorite Productivity App: https://airtable.com/invite/r/2zH40fus/
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https://www.youtube.com/watch?v=or2rELKrukE
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1 year ago
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video/mp4
English
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VIDEO
CUSHI
cushing-syndrome-workup-in-1-minute
??Animated Mnemonics (Picmonic): https://www.picmonic.com/viphookup/medicosis/
- With Picmonic, get your life back by studying less and remembering more. Medical and Nursing students say that Picmonic is the most comprehensive and effective way to bridge learning and test prep...
Disclaimer: I use affiliate links....
►???Antibiotics Lectures: https://www.medicosisperfectionalis.com/products/courses/antibiotics/ ... Check out my brand new "Electrolytes" course at https://www.medicosisperfectionalis.com/products/course/electrolytes/ and use the PROMO code: ELECTROLYTES50 to get a 50% discount. ► Right Now! You can get access to all my hand-written hematology video notes (the notes that I use on my videos) on Patreon...There is a direct link through which you can view, download, print and enjoy! Go to https://www.patreon.com/medicosis How to diagnose Cushing Syndrome in 4 easy steps!
My FAVORITE BOOK to study Pathology and pathophysiology for step 1 USMLE is Goljan, you can check it out here: https://goo.gl/9ojg6M
My favorite book for internal medicine is Harrison's, check it out here: http://amzn.to/2A7UEdj
My favorite book for surgery is this one, which contains notes and vignettes of Dr. Pestana, here: https://goo.gl/UdDGHq
My favorite book for Ob.GYN is Hacker and Moore: https://goo.gl/umFsjc
For a review book for USMLE step 1, check First Aid here: http://amzn.to/2zOU7w2
For a review book to study USMLE step 2CK, I recommend: http://amzn.to/2iI6zue
For a review book to study USMLE step 2CS, check http://amzn.to/2z24RtR
Check this pharmacology book, really easy to read, and inexpensive: Pharmacology made incredibly easy: https://goo.gl/or3DzB
If you would like a good pharmacology textbook, try Lippincott illustrated: https://goo.gl/PYEUP2
(Disclaimer: The medical information contained herein is intended for physician medical licensing exam review purposes only, and are not intended for diagnosis of any illness. If you think you may be suffering from any medical condition, you should consult your physician or seek immediate medical attention.)
Disclaimer: these links are affiliate links, so that I get paid a percentage of the sale, to support the channel, however, the customer is not affected as they pay the same price.
Get ready for your USMLE, NCLEX or COMLEX
Click the Subscribe button to get new videos every week.
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----My website will launch next year, so stay tuned…
My dream is to do white board classroom teaching, audio podcast and live online webinars. But, I need your support to do this.
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https://www.youtube.com/watch?v=qO-c-m5g3hA
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Created
1 year ago
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video/mp4