#beatingcovid19: Daily Dose - R
1. Remdesivir, sold under the brand name Veklury,[3][4] is a broad-spectrum antiviral medication developed by the biopharmaceutical company Gilead Sciences.[5] It is administered via injection into a vein.[6][7] Remdesivir is being tested as a treatment for COVID‑19, and has been authorized for emergency use in the US, India,[8] Singapore,[9] and approved for use in Japan, the European Union, and Australia for people with severe symptoms.[3][4][10][11][12][13] It also received approval in the UK in May 2020; however, it was going to be rationed due to limited supply.[14] It may shorten the time it takes to recover from the infection.[15]
The most common side effect in healthy volunteers is raised blood levels of liver enzymes (a sign of liver problems).[3] The most common side effects in people with COVID‑19 is nausea (feeling sick).[3]
Side effects may include liver inflammation and an infusion-related reaction with nausea, low blood pressure, and sweating.[16] It is a prodrug that is intentended to allow intracellular delivery of GS-441524 monophosphate and subsequent biotransformation into GS-441524 triphosphate, a ribonucleotide analogue inhibitor of viral RNA polymerase.[17]
Earlier studies found antiviral activity against several RNA viruses including SARS coronavirus and MERS coronavirus, but it is not approved for any indication.[5][10] Remdesivir was originally developed to treat hepatitis C[18] and was then tested against Ebola virus disease and Marburg virus disease, but was ineffective for all of these viral infections.[5][19]
Trials are ongoing and some reports are added herein.
Helpful reading
https://en.wikipedia.org/wiki/Remdesivir
https://jamanetwork.com/journals/jama/fullarticle/2769871
https://www.nejm.org/doi/full/10.1056/NEJMoa2007016
2. Regeneron.
This is an antibody cocktail.
Regeneron’s antibodies — REGN10933 and REGN10987 — both target the “spike” protein on the virus’ surface that helps it invade cells, but individually, each drug binds to the protein at a different, non-overlapping location. This “cocktail” approach aims to increase the chance that the virus can be neutralized without escaping. It’s the same multidrug strategy used successfully to treat other viral diseases such as HIV and hepatitis C. Regeneron refers to the dual antibody regimen as REGN-COV2.
Tests are ongoing and phase 3 trial results will be released soon.
https://www.statnews.com/2020/08/11/antibody-drugs-could-be-one-of-the-best-weapons-against-covid-19-but-will-they-matter/
https://www.biopharma-reporter.com/Article/2020/08/11/Regeneron-targets-September-data-drop-from-COVID-19-antibody-trial
3. Response-Ability
That means you are responsible for everything you say and do, and you are i
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https://www.youtube.com/watch?v=avr43b1kQJ0
#beatingcovid19: Daily Dose - T
A. Tests for Covid19
1. A diagnostic test can show if you have an active coronavirus infection and should take steps to quarantine or isolate yourself from others. Currently there are two types of diagnostic tests which detect the virus – molecular tests, such as RT-PCR tests, that detect the virus’s genetic material.
2. Antigen tests that detect specific proteins on the surface of the virus.
3. An antibody test looks for antibodies that are made by your immune system in response to a threat, such as a specific virus. Antibodies can help fight infections. Antibodies can take several days or weeks to develop after you have an infection and may stay in your blood for several weeks or more after recovery. Because of this, antibody tests should not be used to diagnose an active coronavirus infection. At this time researchers do not know if the presence of antibodies means that you are immune to the coronavirus in the future.
What is PCR:
PCR tests the “gold standard” of COVID-19 testing, but, like all tests, they’re not perfect. Studies have suggested as many as 30% of COVID-19 PCR test results are inaccurate. (For comparison, the CDC in 2018 estimated that rapid flu tests have about the same rate of incorrect results.)
Polymerase chain reaction (PCR) is a method widely used to rapidly make millions to billions of copies of a specific DNA sample, allowing scientists to take a very small sample of DNA and amplify it to a large enough amount to study in detail. PCR was invented in 1984 by the American biochemist Kary Mullis at Cetus Corporation.
Helpful reading
https://en.wikipedia.org/wiki/COVID-19_testing
https://www.fda.gov/media/140161/download
https://time.com/5880255/covid-19-tests-types/
B. Testing of your faith
James 1:3-5
Amplified Bible
3 Be assured that the testing of your faith [through experience] produces endurance [leading to spiritual maturity, and inner peace].
4 And let endurance have its perfect result and do a thorough work, so that you may be perfect and completely developed [in your faith], lacking in nothing.
5 If any of you lacks wisdom [to guide him through a decision or circumstance], he is to ask of [our benevolent] God, who gives to everyone generously
and without rebuke or blame, and it will be given to him.
We are all being tested so we can be better not bitter and all tests yield Testimonies.
Accept the tests you must endure because tests are a perfecting work and a developing work.
—Save Lives—-
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Corona Colic 4
In the last part of the series we discuss the RRI
1. Renovate
2. Refurbish
3. Innovate
As we come to the end of the corona lockdown your Return to Business formula should include the RRI
To find out you current business/ work posture you need to ask yourself the following questions
1. Can your business operate in a Social distancing environment? You may need to Renovate or Refurbish Or innovate to comply
2. Can you deliver your products over the net via sae delivery systems? You may need to find ways to safely transit your product ins a safe manner.
3. Do you have an online presence, Not just a website and Fb page? Do people know you? Get in touch for your free tech talk on WhatsApp 0777800580
The corona colic series:
1. Coronaconomics: https://youtu.be/_-Wjt0tmWXQ
2. Corona Colic: Causes and Self reliance: https://youtu.be/aNBRignKonw
3. Corona Colic: Make your business an Essential service: https://youtu.be/wfkV1RMwTok
4. Corona Colic: Add technology to catapult your business: https://youtu.be/sABOabV8Xw8
5. Corona Colic: Renovate/Refurbish/Innovate: https://youtu.be/i72rDVtscR0
We will overcome just like those before us overcame and became Overcomers.
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