Work with a health coach on a monthly basis, and start improving your health from tomorrow. info@superlongevity.net Services of our professionals: health and longevity consultations, health and longevity research for private and business clients, helping you create a personalized protocol for your needs. Contact: info@superlongevity.net Write us to know how to commission the preparation of one or more of the new personalized protocols offered by our professionals: 1) the super longevity protocol; 2) the super immunity protocol; 3) the super energy and mitochondria protocol; 4) the hair loss protocol: 5) rejuvenation T protocol (telomeres age); 6) rejuvenation M protocol (DNA methylation age); 7) sport performance, stamina and endurance protocol; 8) sport performance, testosterone, muscles and strength protocol. For any other queries, feel free to write to info@superlongevity.net and we'll put you in touch with professionals who work with our network. *** IS NMN SAFE IN HUMAN? | Keio University Study on NMN in Human | NMN Human Study *** Tell us about your personal experience in the comment section. We are always thrilled to hear your feedback and experience. *** If you want us to give you the contact information of professionals who work with our network, feel free to write to info@superlongevity.net and we'll put you in touch with the right professional for your needs. In order to better find the right professionals for you, please indicate in your email if your queries regarding: 1) overall health; 2) food and supplement; 3) longevity. 4) others (in this case a brief description of your needs is recommended). We will get back to you as soon as possible with the contact information of a specific provider. *** The Japanese Keio University had a research team that investigated and showed, for the first time, that NMN, an anti-aging intervention compound, is safe to be administered to healthy humans. This research team was led by Professor Kazuo Tsubota of the Department of Ophthalmology, Professor Hiroshi Itoh of the Department of Internal Medicine, Professor Hideyuki Okano of the Department of Physiology, and Professor Masato Yasui of the Department of Pharmacology, along with a collaboration of Washington University School of Medicine in Saint Louis. This is because, in 2015, both universities agreed to conduct joint investigations on subjects such as longevity. The study establishes that “Recent studies in animal models have shown that the administration of NMN increases the amount of nicotinamide adenine dinucleotide (NAD+) in various organs and improves age-associated functional decline and disease conditions. However, the safety of NMN in humans has remained unclear". Since 2016, the research team has conducted a clinical trial study to investigate the safety of single administration of NMN in ten healthy men and has confirmed that it can be safely administered and that it is effectively metabolized in the body. This study is expected to inform future treatment of age-associated diseases. For this study, 10 healthy men aged 40 to 60 years were administered a single dose of 100, 250, or 500 mg of NMN orally. This oral administrations of NMN didn’t produce remarkable changes in blood pressure or in heart rate. Urine and blood tests, used for analyzing kidney and liver function, didn’t exceed the normal levels. Also, these single doses didn’t affect sleep quality nor did they change eye functions. During the measurement of the number of plasma metabolites produced from NMN, the team found said plasma metabolites had increased accordingly to the dosage. From this, it was concluded that orally administered NMN can be metabolized in the human body and is safe to be used at single doses up to 500mg. Past studies investigated treatments for the increase of NAD+ tissue in order to prevent age-related diseases, but, currently, one of the leading candidates for the stimulation of sirtuin1 enzymes, which has a critical role in longevity control in mammalians, is NMN. For the first time, because of this clinical study, it has been shown that NMN is safe for humans and that further development of research about the application of NMN for the treatment of age-related diseases can be expected. The team is also planning a study on the long-term administration of NMN in healthy subjects. We would like to hear about your own experience with this topic. Leave a comment. Lastly, remember that it is important to talk to a doctor or other professional before beginning any sort of supplementation or treatment. Feel free to contact us if you want us to give you the contact information of professionals who work with our network. *** Topic related to: LONGEVITY, HEALTH, IMMUNITY, INFLAMMATION, ANTIAGING, LIFESPAN, Mitochondria, HEALING, SUPPLEMENTS, HEALTHY LIFE, IMMUNE SYSTEM, LONGEVITY PROTOCOL. Contact: info@superlongevity.net ... https://www.youtube.com/watch?v=JQj2paKRY_c