Boosting The Innate Arm of Your Immune System
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Fundamental approach:
Strengthen the epithelial cells
Optimize the production of antimicrobial peptides (AMP)
Optimize the immune cells
Keep the cells well nourished
Reduce the stress hormone/molecules’ effect on these cells
Activate the innate arm as soon as possible with better strength
Exercise
Sleep
Epithelial barrier function improvement with diet
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4377870/
Immunity In Depth | Linus Pauling Institute | Oregon State University
Set of strategies to enhance the innate immune system
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7304486/
Points:
*Phenyl-butyrate and vitamin D help stabilize the lung and the gut epithelium
Antimicrobial peptides AMP: https://en.wikipedia.org/wiki/Antimicrobial_peptides
https://en.wikipedia.org/wiki/Sodium_phenylbutyrate
*Vitamin D promotes the production of macrophages and monocytes, in addition to other immune modulating functions.
*Improve autophagy
Vitamin D helps with autophagy
What cells produce IL-17A?
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3152582/
Gamma delta T Cells - friends or foe?
https://en.wikipedia.org/wiki/Gamma_delta_T_cell
Interferon Gamma induction can cause cancer
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4823949/
Peripheral blood lymphocytes (PBL)
https://en.wikipedia.org/wiki/Peripheral_blood_lymphocyte
BCG Vaccine enhances NK cells activity
https://pubmed.ncbi.nlm.nih.gov/3076601/
Vitamin D
https://youtu.be/prLkrJh38_M
https://youtu.be/wJyT1YSwe-8
Vitamin D is necessary for the production of cathelecidins, beta defensins, and NFkB.
Antibody response bias
Vitamin C
https://youtu.be/WXULPNF6cTI
What is buffered vitamin C?
https://www.nutriadvanced.co.uk/news/confused-about-the-different-types-of-vitamin-c/
Role of vitamin C as an antioxidant
https://pubmed.ncbi.nlm.nih.gov/9248859/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5098518/
Cimetidine and the NK cells
https://pubmed.ncbi.nlm.nih.gov/3076601/
Cimetidine alone can cause NK cells suppression. However, cimetidine with IFN-alpha can enhance NK cells activity.
Forest bathing
https://environhealthprevmed.biomedcentral.com/articles/10.1007/s12199-008-0068-3
https://www.nature.com/articles/s41423-020-0477-9
Reduce adrenaline by relaxing. Forest bathing. Yoga. Exercise.
Psychological intervention
Mindfulness
Resident memory t cells
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6914228/
Targeting resident memory T cell immunity culminates in pulmonary and systemic protection against Brucella infection
NK cell boost
About Natural Killer Cells & How to Increase & Decrease Them - SelfHacked
Complem
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COVID Updates With Paul Bork
Our resident statistician Paul Bork discusses the new variants and their impact. Let's listen in.
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Disclaimer:
This video is not intended to provide assessment, diagnosis, treatment, or medical advice; it also does not constitute provision of healthcare services. The content provided in this video is for informational and educational purposes only.
Please consult with a physician or healthcare professional regarding any medical or mental health related diagnosis or treatment. No information in this video should ever be considered as a substitute for advice from a healthcare professional.
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What is Love? Oxytocin and Other Love Hormones!
Greatest emotional investment of all is falling in love… Happy Valentine’s
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Remember when you love someone and everything looks beautiful. Not only in them but in everything else as well? Everything is sexy, cool, attractive. You are in heaven? There’s no-one better than your beloved in the world, never was, never will be?
Did you realize that it went on for a year, and then the same things starting to fade away? The heaven was not there anymore? The woman says you don’t love me the same as before? The man starts finding other women more attractive than their own mate?
In the beginning the blind love the passionate love, the fire is created by the of releases serotonin, dopamine, and nor-adrenaline. Serotonin, creates the feeling of well being, happiness, and anchoring in the world. Dopamine creates intense focus, motivation, and better recall. Nor-adrenaline increases muscle tone, increased performance, blood pressure, increased heart rate, etc. Collectivley, these hormonones heighten your emotional state and suppress the analytical mind. This magical moment continues for a few months to years. The eventual outcome of this intense bond is the sexual intercourse resulting in the formation of a new being.
The affectionate love is then produced by oxytocin which is released to keep them bonded beyond initial months into a year or so. This way they will take care of the baby. Oxytocin generated love empowers the woman to care for the baby and the man works to raise the family.
For a year, your brain released love, energy, focus, hormones for you. Oxytocin for example is one such powerful hormone.
Some men become addicted to the initial hormone cocktails. That is because they want to experience these hormones again.
Dopamine
So, how do you release dopamine ?
Remember dopamine helps with focus, motivation, memory, emotions, pleasure, reward, sensation, and perception.
Telling suspenseful stories with cliff-hangers release a lot of dopamine.
Let me tell you such a story: my story when I encountered a motorbike that jumped the red-light. Did my bones break?
Oxytocin
Both men and women release oxytocin. Usually when they touch each other. Females release more oxytocin than the men. Females bond strongly, but will take time. This is also why remote relationships are difficult to maintain as the oxytocin release is reduced.
Oxytocin makes you become more generous, it makes you trust more, and you bond to the person that raises your oxytocin.
Remember in women oxytocin i
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Random COVID Questions with Dr. Been (#89)
Let’s discuss your COVID questions.
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Dr. Mobeen discusses the following possible causes of the massive damage caused by SARS-COV-2.
Reduced immunomodulatory function of the ACE2 receptors.
Cytokine storm
Massive inflammation
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Fascinating Questions with Dr. Been (#180)
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Disclaimer:
This video is not intended to provide assessment, diagnosis, treatment, or medical advice; it also does not constitute provision of healthcare services. The content provided in this video is for informational and educational purposes only.
Please consult with a physician or healthcare professional regarding any medical or mental health related diagnosis or treatment. No information in this video should ever be considered as a substitute for advice from a healthcare professional.
...
https://www.youtube.com/watch?v=Erzf_pB6aEM
Dr. Darrell DeMello Discusses COVID Outpatient Management
Today we will have Dr. Darrell DeMello from India. Dr Darrell DeMello has considerable experience with COVID-19. So far, he has treated over 6,000 COVID-19 patients, +24000 family members and provided prophylaxis to another 12,000!.
For our talk today, Dr. Darrell DeMello will share with us about his latest findings when it comes to his therapeutic approaches for COVID-19.
Brief bio:
Dr. Darrell DeMello has some 30 years of experience in the medical field, with tenures at Wyeth Labs (India), American Cyanamid (India), C R Bard (India), Boston Scientific (USA & India), ScyFIX LLC (USA) and Market Access India (USA). He performed a variety of functions for these corporations, such as global sales, marketing, market development, business development, strategic management & general management experience with minimally invasive medical devices in interventional cardiology, vascular surgery/ interventions, cardiac surgery, gastro-enterology/Endoscopy and Ophthalmology class II and III medical devices.
Twitter link: https://twitter.com/drbeen_medical/status/1400158745808621568?s=20
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This is the concluding lecture about the T cells. The function of T helper 1, and 2, cytotoxic T cells, NK cells, and T regulator cells (T17) are discussed.
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Selenium disables protein disulfide isomerase (PDI) enzyme of the viruses.
It helps proliferate Natural Killer cells.
It helps proliferate T lymphocytes in the presence of phytoncides from onions.
Vitamin D, E and Selenium work better together
It reduces thrombosis in the vessels.
It is part of Glutathione to work as an antioxidant
Selenium and COVID-19
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7246001/
Selenium with Ebola virus
http://www.sciencedomain.org/download/NzI3NkBAcGY.pdf
Functions of PDI
https://www.researchgate.net/figure/Thiol-disulfide-exchange-reactions-between-protein-disulfide-isomerase-PDI-proteins-and_fig6_51853364
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https://www.youtube.com/watch?v=KgI-0rJCwh8