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19 Jul 2021 03:59:06 UTC
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New COVID Strain Update: Will Vaccines and Ivermectin be effective against new COVID Strains?
New COVID Strain Update: Will Vaccines and Ivermectin be effective against new COVID Strains? UK Variant and South African Variant Explained

Viruses constantly mutate, new variants and strains emerge, and multiple variants of covid have already been documented. The term “strain” is specific to the virus, SARS-CoV2, but not COVID, the disease. The term “variant” is used to classify viruses that have developed a specific group of mutations that causes them to behave differently than the strain it originated from. So far, scientists are classifying the new mutations found in the UK, South Africa, Nigeria, and Brazil as “variants.” Some suggest that the South African variants, 501Y.V2, are very concerning and should be classified as a new strain.

With the recent rollout of the Pfizer and Moderna mRNA vaccines, the biggest questions on everyone’s minds are “will these variants affect the vaccine efficacy” and “are these new variants more infectious”? While researchers are optimistic that the current vaccines will be effective against the UK variant, there is growing concern over the South African variant.

So in this video, I will be going over these new covid variants and, more importantly, addressing vaccines' concerns and current medication effectiveness.

According to reports, the UK variant, B.1.1.7, was first detected in September. Still, it wasn’t until mid-December that health officials noted rapid spread through the UK, especially in London and southeast England. This variant has a vast number of mutations, especially in the receptor-binding domain, N501Y, in the spike protein that causes the virus to bind more readily to the ACE2 receptors and spread more easily than other variants and has now been detected in the United States and Canada.

The South African variant, 501Y.V2, was originally detected in early October 2020 and is now the predominant variant, overwhelming hospitals, and South Africa mortality. While it shares some mutations with the UK variant, the south African variant carries a specific mutation in the receptor-binding domain of the virus’s spike protein called E484K. The UK variant doesn’t have.
This is an important site because neutralizing antibodies induced by infection or vaccination binds to the virus. As a result, some scientists worry that vaccines could be less effective in the South Africa variant. In the past few weeks, this variant has been detected in Finland, UK, Australia, Japan, South Korea and is now the dominant strain in Zambia. However, there are no reports today that it has been detected in the US, but in my opinion, it is just a matter of time before we see this strain in the US.

Papers mentioned in the video:
https://www.biorxiv.org/content/10.1101/2020.12.31.425021v1
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https://www.youtube.com/watch?v=VZvXYE1mGWI
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