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122126
Author: Daniel M. Davis
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The immune system holds the key to human health. In The Beautiful Cure, leading immunologist Daniel M. Davis describes how the scientific quest to understand how the immune system worksand how it is affected by stress, sleep, age, and our state of mindis now unlocking a revolutionary new approach to medicine and well-being. The bodys ability to fight disease and heal itself is one of the great mysteries and marvels of nature. But in recent years, painstaking research has resulted in major advances in our grasp of this breathtakingly beautiful inner world a vast and intricate network of specialist cells, regulatory proteins, and dedicated genes that are continually protecting our bodies. Far more powerful than any medicine ever invented, the immune system plays a crucial role in our daily lives. We have found ways to harness these natural defenses to create breakthrough drugs and so-called immunotherapies that help us fight cancer, diabetes, arthritis, and many age-related diseases, and we are starting to understand whether activities such as mindfulness might play a role in enhancing our physical resilience. Written by a researcher at the forefront of this adventure, The Beautiful Cure tells a dramatic story of scientific detective work and discovery, of puzzles solved and mysteries that linger, of lives sacrificed and saved. With expertise and eloquence, Davis introduces us to this revelatory new understanding of the human body and what it takes to be healthy. **Review The Beautiful Cure sets the stage for a coming revolution in immunology, with fascinating stories of how researchers solved puzzles they didnt know existed. (Jeremy Webb New Scientist) A terrific book by a consummate storyteller and scientific expert considers the past and future of the bodys ability to fight disease and heal itself. . . . We should all pay more attention to understanding the barricades that evolution has provided us with, that we have learned to train, because this war is endless. The Beautiful Cure is a worthy guide. (Adam Rutherford Guardian) Five stars. We all think we know, at a rough level, how the immune system works. Cells in the blood identify foreign invaders and go into battle with them. Inflammation and perhaps a fever develop, and eventually the body destroys the illegal immigrants. From then on their card is marked the system remembers the microscopic terrorists, and if they ever reappear they are ganged up on and eliminated immediately. Thats immunity. In recent decades, though, the scientific picture has become hugely more complicated, as the immunologist Davis relates in this elegantly concise book. (Steven Poole Telegraph) Daviss wonderful book The Beautiful Cure recounts how research into the immune system in recent decades has resulted in what amounts to a health revolution. Immunotherapy drugs are now worth billions of dollars, and cancers and autoimmune diseases that were once considered untreatable can now be fought and, in a few cases, even cured. There is little doubt that there will be further progress in the years to come. Davis recounts in exceptionally clear and sympathetic prose how all this came about. (Henry Marsh New Statesman) Forget AI, robotics, the internet of things. This is where the future feels strange and exciting in ourselves, in the inner universe of our messy, complex immune system, and in the radically new therapies that are using it to conquer disease. Davis is passionate about the possibilities of his field. . . . He describes how these cells perform with the fervor of an enraptured dance critic. . . . Davis is right to call the immune system an inner universe. It is just as consciousness-raising and awe-inspiring as the outer universe of black holes and supernovas, yet far less widely known or understood. This eye-opening if demanding book starts to put that right. (James McConnachie Sunday Times) The Beautiful Cure is about the history and future of immunology. It is a sweeping tour dhorizon that never shies from complexity but manages, impressively for a science book by a scientist, to remain lucid and entertaining enough to take the reader with it. Much as Siddhartha Mukherjee did in his book The Gene, Davis expertly weaves together human stories and scientific endeavor to give a sense of the grand global collaboration that is still under way to understand the complexity, delicacy, and elegance of our immune system. . . . If anything can be taken from this book it is that life and its mechanisms are too complex for neat stories, however satisfying those stories may be. (Tom Whipple Times) Davis is a sure and engaging guide to these developments. . . . In each case, Davis shows how these scientific thinkers overturned the previous dogma and progressively deepened the story of immunology. His message is that although knowledge of the immune system has come on in leaps and bounds in the past hundred years, immunology still lacks a unifying theory. We must not expect everything the immune system does to fit any one over-arching principle, he concludes. The system discriminates between self and non-self, and it detects germs, and it responds to danger, and it does all these things concurrentlyand messily. (Mark Honigsbaum Observer) An inspirational book that not only reveals the secret joys of scientific discovery but is jam-packed full of revelations for non-scientists. (Jon Dennis Mail on Sunday) A laymans introduction to the current state of the science of immunology. It is not an easy read, not because Davis is wilfully obscure but because his subject matter is extremely complex. Explanations should be as clear as possible, but not clearer than possible. (Anthony Daniels Literary Review) Brilliantly conveys the excitement of scientific discovery. (Bill Bryson) About the Author Daniel M. Davis is professor of immunology at the University of Manchester in the UK. He is the author of The Compatibility Gene How Our Bodies Fight Disease, Attract Others, and Define Our Selves, which was picked by Bill Bryson for the Guardians**Books of the Year feature.
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101170
Author: Stuart A. Wright
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This book explores an escalating spiral of tension between the Patriot movement and the state leading up to the Oklahoma City bombing in 1995. The author served as a consultant to Timothy McVeighs defense team and draws on information based on face-to-face interviews with McVeigh. Wright contends that McVeigh was firmly entrenched in the Patriot movement and was part of a network of warrior cells that planned and carried out the bombing. By examining the Patriot movements history and subsequent reconfiguration of conflicts with the state, McVeighs role in the bombing can be more fully understood.ReviewWhy did domestic terrorism on the scale of the 1995 Oklahoma City bombing occur? [Patriots, Politics, and the Oklahoma City Bombing] shows how convicted bomber Timothy McVeigh and his co-conspirators rose up from an increasingly militant Patriot social movement that promoted leaderless resistance by phantom cells in a spiraling war with U.S. law enforcement agencies - themselves increasingly militarized through gun raids and the war on drugs. By exploring the deep historical connections of the Patriot movement to Cold-War anti-communism, racist opposition to the Civil Rights movement, the anti-tax movement, the farm crisis, and opposition to gun control, Stuart Wrights gripping and forceful account brings to light the social dynamics of a deeply troubling variant of right-wing political culture that America needs to understand and confront. John R. Hall, University of California - Davis, Author, Apocalypse ObservedThis book should be read by anyone concerned to understand how terrorism, decidedly unrelated to Islamo-fascism, has arisen in contemporary America. The portrait of Timothy McVeigh is riveting in its own way, but he is, for better or worse, safely dead. What is most disturbing is the suggestion that the current US armed forces may in effect be serving as a training camp for future McVeighs who may, for whatever complex of reasons, feel a similar alienation from their government. Sanford Levinson, University of Texas, Author, Our Undemocratic Constitution Where the Constitution Goes Wrong (and How We the People Can Correct It)The story of the Oklahoma City bombing is one that Stuart Wright is uniquely qualified to tell because of his masterful understanding of the Patriot movement, partly based on personal interviews with Timothy McVeigh. Combining the skills of a historian, a sociologist, and a detective, Wright places this cataclysmic event in the complex context of broad developments since the end of World War II and the specific policies, individual actions, and government responses that led up to the bombing. The result is a remarkably compelling analysis of the fateful social and political dynamics that brought McVeigh and his truckload of explosives to Oklahoma City. This book is an informative, insightful, and gripping study that is at once irresistibly fascinating and deeply disturbing. Carl Smith, Northwestern UniversityStuart Wrights book provides a fascinating insight into the Christian Patriot movement by centering on the Oklahoma City bombing. Wright draws on many personal interviews to create an account of a spiral of threat and opportunity that is a contribution to the theory of social movements. The book will be of interest to sociologists, political scientists, historians, and all others who study violent social movements. Clyde Wilcox, Georgetown UniversityIn our post 911 world it is too easy to forget that there is a significant, armed, militant, domestic anti-government movement -- one that is also willing to use terrorist tactics. Wrights book is a useful and intellectually engaging reminder. Wright weaves together a nuanced story of how the anti-communism of the 50s, resistance to the civil rights movements of the 60s, the anti-tax backlash of the 70s, and the farm crisis of the 80s combined with a burgeoning gun culture to produce a movement that conceives of itself as at war with its own government in order to save its nation. This movements ideology has been abetted and facilitated by a federal government that has declared war on drugs, crime, and terrorism, militarized the police, and expanded the domestic role of the military. Those interested in the far right, Patriot movement militias, and issues of terrorism in the contemporary world should not miss this book. Rhys H. Williams, University of Cincinnati, Editor, Cultural Wars in American Politics Book DescriptionThis book explores an escalating spiral of tension between the Patriot movement and the state leading up to the Oklahoma City bombing in 1995. The author served as a consultant to Timothy McVeighs defense team and draws on information based on face-to-face interviews with McVeigh. This book explores social movements by analyzing an escalating spiral of tension between the Patriot movement and the state centered on the mutual framing of conflict as warfare. By examining the social construction of warfare as a principal script or frame defining the movement-state dynamic, Stuart A. Wright explains how this highly charged confluence of a war narrative engendered a kind of symbiosis leading to the escalation of a mutual threat that culminated in the Oklahoma City bombing. Wright offers a unique perspective on the events leading up to the bombing because he served as a consultant to Timothy McVeighs defense team for eighteen months and draws on primary data based on face-to-face interviews with McVeigh. The book contends that McVeigh was firmly entrenched in the Patriot movement and was part of a network of warrior cells that planned and implemented the bombing.
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English