BROWSE The Internet EASY way with The Audiopedia owned Lightina Browser Android app. INSTALL NOW - https://play.google.com/store/apps/details?id=com.LightinaBrowser_8083351 What is ANAPHASE LAG? What does ANAPHASE LAG mean? ANAPHASE LAG meaning - ANAPHASE LAG definition - ANAPHASE LAG explanation. Source: Wikipedia.org article, adapted under https://creativecommons.org/licenses/by-sa/3.0/ license. One of many ways to induce Aneuploidy, Anaphase Lag is a mechanism by which a sister chromatid is lost through the course of cell division due to improper spindle formation and subsequent segregation of chromatids. This event can occur during both meiosis and mitosis with unique repercussions. In either case, anaphase lag will cause one daughter cell to receive a complete set of chromosomes while the other lacks one paired set of chromosomes, creating a form of monosomy. The survival of this monosomic daughter cell will depend on which sister chromatid has been lost as well as the background genomic state of the cell. The passage of abnormal numbers of chromosomes will have unique consequences with regards to mosaicism and development as well as the progression and heterogeneity of cancers. There are two notable mechanisms that cause Anaphase Lag, each of which are characterized by merotelic attachments of kinetochores to the microtubules responsible for chromatid separation. Merotelic attachments occur when a single centromere kinetochore attaches to microtubules originating from both spindle poles of the dividing cell. The merotelic attachments can occur in two ways: centrosome spindle attachments from both poles on the same chromatid kinetochore or the formation of a third centrosome whose microtubule spindles attach to a chromatid kinetochore. Because the chromatid is being pulled in two opposing directions or away from the correct centriole, it cannot migrate to the mass of segregated chromatids at either pole. If the migration is significantly delayed the reformation of nuclei will begin to occur without a full complement of chromosomes. This nuclear envelope formation is also seen for the lone lagging sister chromatid, forming a micronucleus. The micronucleus has the capacity to persist in the daughter cell but with abnormal replication and maintenance machinery. This allows for the accumulation of mutations, increasing the potential for future miss-segregation events. In total these events cause problematic aneuploid cells with increased genomic instability. This has important implications in the development and persistence of cancers as well as debilitating developmental diseases. ... https://www.youtube.com/watch?v=LWhF2jDOWac

BROWSE The Internet EASY way with The Audiopedia owned Lightina Browser Android app. INSTALL NOW - https://play.google.com/store/apps/details?id=com.LightinaBrowser_8083351 What is MIDDLE-MARKET COMPANY? What does MIDDLE-MARKET COMPANY mean? MIDDLE-MARKET COMPANY meaning - MIDDLE-MARKET COMPANY definition - MIDDLE-MARKET COMPANY explanation. Source: Wikipedia.org article, adapted under https://creativecommons.org/licenses/by-sa/3.0/ license. Authorities provide differing definitions of the middle-market or mid-market companies. While some authorities look to revenue generated by companies to define the middle market, other sources regard either asset size or number of employees as a better metric for comparing company sizes. Definitions of the middle market are generally derived by dividing the United States economy into three categories: small business, middle-market, and big business. According to figures collected by the U.S. Census Bureau, the total revenue of all U.S. businesses in 2012 was roughly $32.6 trillion. The largest of these companies, which are big businesses with revenue of over $3 billion, make up roughly one-third of that total, and businesses with a revenue of under $100 million made up about another third of the total revenue. The middle market can thus be defined as the companies larger than small businesses but smaller than big businesses that account for the middle third of the U.S. economy’s revenue. Each of these companies earns an annual revenue of between $100 million and $3 billion. ... https://www.youtube.com/watch?v=EkxvZXP3r_4

How to say THE TROOP in Spanish? What is the Spanish word for THE TROOP? ... https://www.youtube.com/watch?v=7QekBZHjMCA

What is FULL DEPTH RECYCLING? What does FULL DEPTH RECYCLING mean? FULL DEPTH RECYCLING meaning - FULL DEPTH RECYCLING definition - FULL DEPTH RECYCLING explanation. SUBSCRIBE to our Google Earth flights channel - http://www.youtube.com/channel/UC6UuCPh7GrXznZi0Hz2YQnQ?sub_confirmation=1 Source: Wikipedia.org article, adapted under https://creativecommons.org/licenses/by-sa/3.0/ license. Full depth recycling or full depth reclamation (FDR), is a process that rebuilds worn out asphalt pavements by recycling the existing roadway. Old asphalt and base materials are pulverized using a specialized machine called a reclaimer. On top of the pulverized material, water is added to reach the optimal moisture content for compaction and then a variety of materials, such as dry cement, lime, fly ash, or asphalt emulsion are incorporated for stabilization. A reclaimer is used again to mix all the materials. After shaping and grading, the new base is compacted to produce a strong, durable base for either an asphalt or concrete surface. ... https://www.youtube.com/watch?v=prQTTMt4dGM