James Halliday designs a virtual reality and hides the keys to his fortune in it for a worthy player to find after his death. Wade, a teenager, sets out on a quest to find the keys and the fortune.
When his former superior, Colonel Samuel Trautman, asks him to join him on a special mission in Afghanistan, Rambo declines. But when Trautman is held hostage and tortured, Rambo decides to step in.
Selene, a vampire warrior, is entrenched in a conflict between vampires and werewolves, while falling in love with Michael, a human who is sought by werewolves for unknown reasons.
During the Cold War, fellow mutants Charles Xavier and Erik Lehnsherr join forces with other mutants to save humanity from a nuclear attack and a possible world war.
Amidst a mission, Vers, a Kree warrior, gets separated from her team and is stranded on Earth. However, her life takes an unusual turn after she teams up with Fury, a S.H.I.E.L.D. agent.
Alice wakes up in the Raccoon City hospital after the area has been overrun by zombies, and must now make it out of the city before a nuclear bomb is dropped.