#Join us as we go over our top stories from the week: Janssen & PRA Design First Truly 100% Mobile Virtual Trial. Henry Ford Hospital #Dermatology Research Probes Laser. 23andMe Officially a Drug Development Operation Licensing Psoriasis Antibody to Almirall. Temple University & Genentech Collaborate on Alternative Opioid Pain Treatments. Transgene and NEC Start Two Clinical Trials with TG4050, an AI-Powered Cancer Vaccine for Ovarian and Head & Neck Cancers. A Billionaire’s ‘Cancer Moonshot’ Comes Down to Earth: But Could it Ever Really Fly? Merck’s Keytruda Shows Mixed Results in Phase 3 Lung Cancer Trial. New Experimental Vaccine for Acute Myeloid Leukemia Evidences Potential During Phase I/II Study at Oslo University Hospital. Houston Methodist Joins IBD Diagnostic Clinical Trial to Accelerate Patient Enrollments & Keep Timelines. Sunshine Coast’s USC Research Coordinators Developing A Consumer Confidence for Clinical Trials. Alliance Research Center Phase 1b Site for First Controlled Clinical Trial for a CRISPR Enhanced Bacteriophage Therapy. Pfizer Rare Disease Lead on the Importance of Clinical Trials to Pursue Rare Disease Treatments. Incyte Announces Phase 3 Study of Itacitinib in Patients with Treatment-Naïve Acute Graft-Versus-Host Disease Fails to Meet Endpoint. Veeva Committed to Solving Systems Challenges at the Principal Investigator Site for More Sustainable Outcomes. Endless Ethical Quandary Created by High Drug Prices. CONNECTED WORLD 00:30 AUTOIMMUNE DISEASE 01:16 OPIOID USE NEWS 02:24 CANCER 02:57 CLINICAL TRIAL 05:55 CLINICAL CHALLENGE 08:59 ... https://www.youtube.com/watch?v=1rrez1ihnOY

Escalating tensions in Eagle Pass, Texas, where the Texas National Guard has taken unprecedented action by seizing control of Shelby Park and denying U.S. Border Patrol agents entry. Governor Greg Abbott's emergency order has sparked a legal battle with the federal government, challenging the state's authority over immigration enforcement. This bold move comes in response to allegations of Border Patrol agents cutting state-installed razor wire, intended to curb illegal immigration. With a record 2.5 million border crossings in 2023, Texas stands firm in its efforts to manage the crisis, despite federal criticism. ... https://www.youtube.com/watch?v=iDFiEcrRZPQ

Join The Conversation! | https://trialsitenews.com/ The French National Authority for Health (HAS) recently recommended that a bivalent omicron booster dose of the mRNA COVID-19 vaccines be available this fall for persons deemed at risk, from the elderly to the immunocompromised, as this Western European nation moves to an annual paradigm similar to the influenza vaccine. Persons that French health authorities suggest should consider a booster include individuals aged 65 years and up, persons diagnosed with comorbidities, pregnant women, and immunocompromised as well as regulatory persons in constant contact with the latter, such as health professionals. ... https://www.youtube.com/watch?v=jDZqr2ZTJmw

00:41 - University of Kentucky Embraces #Ivermectin & Other Experimental Medications in ‘Pick-the-Winner’ COVID-19 Trial: Clinical leaders from the University of Kentucky Markey Cancer Center College of Medicine and College of Pharmacy are now embarking on a novel path to investigate #COVID-19 therapies. In a first in the United States, a major academic medical center has taken on Ivermectin as an experimental therapy targeting SARS-CoV-2, the virus that causes COVID-19—along with azithromycin and camostat mesilate. These drugs all could potentially inhibit replication of SARS-CoV-2. All three of these therapies will be tested alone or in combination with the antimalarial drug #hydroxychloroquine. In a “pick-the-winner” trial, innovation and pragmatic experimentation meet clinical research collaboration in the Bluegrass State. 00:42 - Contact Tracing India-Style: Despite the Risks of COVID-19, Privacy Advocates are Concerned: Countries moving to pivot out of the COVID-19 pandemic lockdowns. Many turn to various strategies involving testing and contact tracing schemes to not only contain infections, but also track and mitigate risk moving forward. Hence a number of nations have established mobile tracing app initiatives from China and Singapore to EU members and Australia. For example—in America, Apple and Google have come together to develop a software app solution designed to on the one hand introduce contact tracing features, but on the other hand preserve user privacy and prevent government intrusion. However The approach in India has some privacy advocates alarmed as data privacy laws are lax and sweeping orders impose mandatory downloads for many. In the country of 1.3 billion, a government-run smartphone app utilizes location service and a central database to evaluate infection risk, but critics warns of the danger civil liberties, as those who do not comply risk punishment from authorities. 09:06 - Does the BCG Vaccine Blunt the Effects of COVID-19? Texas A&M Chancellor Makes an Investment to Find out: In our final story for this Episode of the Weekly Round-up, Researchers have noted an interesting possible association: as the COVID-19 spread the morbidity and mortality rates appeared to be lower in some developing countries where the BCG vaccine is widely used. Texas A&M investigators are recruiting hundreds of frontline medical workers to participate in a late-stage, Phase 4, clinical trial of a widely used vaccine that could blunt the effects of COVID-19. Chancellor John Sharp offered $2.5 million to help the study. The Aggie researchers are the first U.S. institution in the clinical trial to have federal clearance for testing on humans ... https://www.youtube.com/watch?v=tRUMYMJVt8c