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6 Jan 2021 00:24:50 UTC
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Author: Edward Edelson
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The names of James Watson and Francis Crick are bound together forever because the scientific discovery they made was truly a joint enterprise. As Edward Edelson reveals in this intriguing biography, Watson and Crick were the first to describe the structure of deoxyribonucleic acid, or DNA, the molecule that carries our genes and determines everything from the color of our eyes to the shape of our fingernails. Even though Watson and Cricks collaboration lasted only a few years, their achievement was enough to tie their names together forever in the history of science and to establish a firm footing for what was then a radical new branch of science molecular biology. In doing so, they paved the way for the early detection of genetic diseases such as sickle-cell anemia, and for new scientific leaps such as animal cloning.From School Library JournalGrade 9 Up-Crick and Watsons long and, at times, frustrating investigative work before discovering the double helix is related here in detail. While the mens genius is revealed, Edelson is also careful to present their human faults and flaws. He discusses Watsons well-known feuds with Rosalind Franklin, a major contributor to his and Cricks research, and, later, with National Institutes of Health director Bernardine Healy. The balanced presentation also credits the research of earlier scientists, providing evidence that each breakthrough was based on the work of many individuals and with the cooperation of colleagues. Along the way, substantial sidebars on Mendelian Genetics sickle-cell anemia cloned mammals and even the invention of the Waring Blendor, used to separate molecular components in cells, supplement the technically detailed chapters. Black-and-white photos and simple illustrations appear throughout. They are not as informative as the graphics found in Linda Tagliaferros Genetic Engineering (Lerner, 1997). Nonetheless, the combined views of scientists as real people rather than idealized heroes with the tedious minutiae of scientific investigation make this a realistic picture of modern research.Ann G. Brouse, Big Flats Branch Library, NY 1998 Reed Business Information, Inc. From Kirkus ReviewsThis latest addition to the Portraits in Science series is somewhat disjointed and unfocused. Edelson attempts to cover the lives of two extraordinary scientists from very different backgrounds who came together for a brief period of time (three years) and were considered the first to describe the structure of DNA in 1953. James Watson, an American biochemist from Chicago, met Francis Crick, an older British physicist, at the Cavendish Laboratory of Cambridge University in England in 1951. Both brilliant, their genius was in their collaboration in codedetermining the structure of the molecule that made up human genes, deoxyribonucleic acid, abbreviated as DNA. The tone of the book is both direct and complex, e.g.,codeNow Watson and Crick had their model two DNA chains, coiled as alpha helixes 20 angstrom units in diameter, making a complete turn every 34 angstrom units, with the bases in each chain 3.4 angstrom units apart. An already complicated portrait of Watson and Crick is further diffused by sidebars on the topics of Mendelian genetics, the Waring Blendor, solving the Sickle-cell puzzle and the first cloned mammals. Well-versed scientists may find this volume interesting however, others will find it just too difficult. (b&w photos and drawings, chronology, further reading, index) (Nonfiction. 12-15) -- 1998, Kirkus Associates, LP.
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