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Explaining Devil's Breath (Scopolamine) from Angel's Trumpets (Brugmansia)
Wrote a small blog post on the topic here: http://stuartoswald.com/2015/02/vice-colombias-scopolamine-devils-breath-drug.html
Here I am introducing a variation of the Angel's Trumpet plant. The flower from which the Devil's Breath Drug is obtained from. Before you all start hammering me on any errors made (I know there's a few technicalities). All I really wanted to do was introduce yourselves to this and show you the plant in it's enviroment.
Scopolamine (USAN), also known as levo-duboisine and hyoscine, sold as Scopoderm, is a tropane alkaloid drug with muscarinic antagonist effects. It is among the secondary metabolites of plants from Solanaceae (nightshade) family of plants, such as henbane, jimson weed (Datura), angel's trumpets (Brugmansia), and corkwood (Duboisia). Scopolamine exerts its effects by acting as a competitive antagonist at muscarinic acetylcholine receptors, specifically M1 receptors; it is thus classified as an anticholinergic, antimuscarinic drug. (See the article on the parasympathetic nervous system for details of this physiology.)
Its use in medicine is relatively limited, with its chief uses being in the treatment of motion sickness and postoperative nausea and vomiting.
Scopolamine is named after the plant genus Scopolia. The name "hyoscine" is from the scientific name for henbane, Hyoscyamus niger. -
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Here I am introducing a variation of the Angel's Trumpet plant. The flower from which the Devil's Breath Drug is obtained from. Before you all start hammering me on any errors made (I know there's a few technicalities). All I really wanted to do was introduce yourselves to this and show you the plant in it's enviroment.
Scopolamine (USAN), also known as levo-duboisine and hyoscine, sold as Scopoderm, is a tropane alkaloid drug with muscarinic antagonist effects. It is among the secondary metabolites of plants from Solanaceae (nightshade) family of plants, such as henbane, jimson weed (Datura), angel's trumpets (Brugmansia), and corkwood (Duboisia). Scopolamine exerts its effects by acting as a competitive antagonist at muscarinic acetylcholine receptors, specifically M1 receptors; it is thus classified as an anticholinergic, antimuscarinic drug. (See the article on the parasympathetic nervous system for details of this physiology.)
Its use in medicine is relatively limited, with its chief uses being in the treatment of motion sickness and postoperative nausea and vomiting.
Scopolamine is named after the plant genus Scopolia. The name "hyoscine" is from the scientific name for henbane, Hyoscyamus niger. -
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