Von-Willebrand factor (vWF) comes from the meagakaryocytes (bone marrow) as well as the Weibel-Palade bodies (endothelial cells). Von Willebrand factor (vWF) helps the platelets adhere to the sub endothelial collagen via GP1b receptor on the platelet. Von Willebrand disease (vWD) is the most common inherited bleeding disorder worldwide. Primary hemostasis involves forming a platelet plug (thrombocytes) whereas secondary hemostasis involves making a fibrin thrombus (coagulation factors). Ionized calcium helps blood coagulate. We test for primary hemostasis via platelet count, bleeding time, and platelet aggregometry. We test secondary Hemostasis via prothrombin time (PT), activated partial thromboplastin time (aPTT), and the old coagulation time (or clotting time, or thrombin time). Von Willebrand Dusease (vWD) affects primary as well as secondary Hemostasis. Hemolytic Uremic Syndrome (HUS), atypical Hemolytic Uremic Syndrome (aHUS), and Thrombotic Thrombocytopenic Syndrome (TTP). Atypical hemolytic uremic syndrome (aHUS) is similar to thrombotic thrombocytopenic Purpura (TTP). Typical Hemolytic Uremic Syndrome (HUS) is a triad of microangiopathic hemolytic anemia, thrombocytopenia, and acute renal failure. Thrombotic thrombocytopenic purpura (TTP) is a pentad of microangiopathic hemolytic anemia, thrombocytopenia, acute renal failure, fever, and neurological abnormalities. ? Get my Anti-Cancer Pharmacology Course: https://www.medicosisperfectionalis.com/products/courses/pharmacology/anticancer/ Use the Promo Code: 35OFFCANCER to get a 35% discount on any product (only 6 left). ? Cardiac Pharmacology Lectures: https://www.medicosisperfectionalis.com/products/cardiac-pharmacology-course ... — ?Antibiotics Lectures: https://www.medicosisperfectionalis.com/ Bernard-Soulier Syndrome (BSS) is an autosomal recessive (AR) disorder characterized by a defective GP1b platelet receptor leading to a problematic platelet adhesion process (primary hemostasis). Glanzmann Thrombasthenia (GT) is an autosomal recessive defect in the GPIIb/IIIa (GP2b/3a) receptor on the platelet which leads to defective platelet aggregation. Ristocetin Cofactor Assay (RIPA) is usually abnormal in cases of Bernard-Soulier Syndrome (BSS). Bleeding time is prolonged, platelets are big in size, but few in number (Macrothrombocytopenia). ??Animated Mnemonics (Picmonic): https://www.picmonic.com/viphookup/medicosis/ - With Picmonic, get your life back by studying less and remembering more. Medical and Nursing students say that Picmonic is the most comprehensive and effective way to bridge learning and test prep... Picmonic has hundreds of animated medical mnemonics...These are very interactive Picmonics that help you memorize and retain tons of ... https://www.youtube.com/watch?v=D0ahHF9oNY0

??Animated Mnemonics (Picmonic): https://www.picmonic.com/viphookup/medicosis/ - With Picmonic, get your life back by studying less and remembering more. Medical and Nursing students say that Picmonic is the most comprehensive and effective way to bridge learning and test prep... Disclaimer: I use affiliate links.... ►?‍??Antibiotics Lectures: https://www.medicosisperfectionalis.com/products/courses/antibiotics/ ... Check out my brand new "Electrolytes" course at https://www.medicosisperfectionalis.com/products/course/electrolytes/ and use the PROMO code: ELECTROLYTES50 to get a 50% discount. ► Right Now! You can get access to all my hand-written hematology video notes (the notes that I use on my videos) on Patreon...There is a direct link through which you can view, download, print and enjoy! Go to https://www.patreon.com/medicosis Smudge cells...Can you describe them? To get access to my videos before anyone else...Go to my patreon page www.patreon.com/medicosis Thanks for watching… Please subscribe. ► PLEASE SUPPORT MY CHANNEL ON “PATREON” TO GET EARLY ACCESS TO MY VIDEOS, PLUS OTHER MATERIALS AND NOTES https://www.patreon.com/medicosis Don’t forget to check my recommended collection of the best medical books that I personally use https://www.amazon.com/shop/medicosisperfectionalis MEDICAL Sources that I use for my videos:- ► Goljan Rapid Review Pathology, https://amzn.to/2MufTPw ► Harrison’s Internal Medicine https://amzn.to/2OJiVNf ► Goldman-Cecil Medicine https://amzn.to/2N0v93u ► Davidson’s Principles and Practice of Medicine https://amzn.to/2vTmf1p ------------------------------------------------------------------------- Many people ask me “How do you record your videos”? Here is the answer:- Equipment that I use:- ► Apple iPad Pro https://amzn.to/2nKCyZW ► Apple pencil https://amzn.to/2PimMCc ►Iphone holder kit: https://amzn.to/2OVV3aj ►Rode Video Mic Go: https://amzn.to/2OVF4Je ►Rode SC7 3.5mm TRS to TRRS Patch Cable: https://amzn.to/2vu2WeY ►Extension Audio Cable https://amzn.to/2nIDApo ►Rode DDC-GO DeadCat Artificial Fur Wind Shield for VideoMic GO: https://amzn.to/2OpbV8m Disclaimer 1: The medical information contained herein is intended for educational purposes only, and are not intended for diagnosis of any illness. If you think you may be suffering from any medical condition, you should consult your physician or seek immediate medical attention. I am NOT a licensed physician…Talk to your doctor. Disclaimer 2: these links are affiliate links so that I get paid a percentage of the sale, to support the channel, however, the customer is not affected as they pay the same price. Got a question? Ask it in the comments section below, or connect ... https://www.youtube.com/watch?v=HCksMPWJQKs

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Anti-DNase Antibody test for Streptococcus pyogenes (Skin infections, Throat infections “Strept throat”, Rheumatic Fever, and acute post-streptococcal glomerulonephritis- Flesh eating bacteria “cellulitis, fasciitis”, and other pyogenic streptococcal infections) | Lab? ?? Antibiotics Course: https://www.medicosisperfectionalis.com/products/courses/antibiotics/ ? ? Kidney Physiology Course: https://www.medicosisperfectionalis.com/products/ ? ObGyn Highyields Course: https://www.medicosisperfectionalis.com/ ? Emergency Medicine HighYields Course: https://www.medicosisperfectionalis.com/ ? Surgery HighYields Course: https://www.medicosisperfectionalis.com/ ? ? Toxicology Course: https://www.medicosisperfectionalis.com/ ❤️ Cardiac Pharmacology Course: https://www.medicosisperfectionalis.com/ ?Acid-Base Course: https://www.medicosisperfectionalis.com/products/ ? Autonomic Pharmacology Course: www.medicosisperfectionalis.com/ ? Electrolytes Course: https://www.medicosisperfectionalis.com/ ? Endocrine Pharmacology Course: https://www.medicosisperfectionalis.com/products/ ? CNS Pharmacology Course: https://www.medicosisperfectionalis.com/ ? General Pharmacology (Pharmacokinetics and Pharmacodynamics): https://www.medicosisperfectionalis.com/ ? Download my handwritten notes: www.medicosisperfectionalis.com/ ⁉️ Questions and Answers: https://www.medicosisperfectionalis.com/ ? Complete the Survey: https://airtable.com/shrYWjvabooT7DrcG ?Free Stuff: https://www.medicosisperfectionalis.com/ ? Pharmacology Lectures: https://www.medicosisperfectionalis.com/ YouTube PLAYLISTS: ► ? Physiology Playlist: https://www.youtube.com/watch?v=6qk_LTVXZ2w&list=PLYcLrRDaR8_eAjmngd289ghWijs2wfqnj&index=2&t=0s ? ? Microbiology and Infectious Diseases Playlist: https://youtube.com/playlist?list=PLYcLrRDaR8_ftu9ms-ytDewlhJxYNuIYo/ ► ? hematology videos: https://www.youtube.com/playlist?list=PLYcLrRDaR8_eoNz6dxXolh1XMEietcniU ► ? Rheumatology: https://www.youtube.com/playlist?list=PLYcLrRDaR8_ckdsow-7buX1rIzIEKfxZQ ► ❤️ Cardiac Pharmacology: https://www.youtube.com/playlist?list=PLYcLrRDaR8_e3pM6ifeZDfNPlE3K4KF3J/ ► Biochemistry ? : https://youtube.com/playlist?list=PLYcLrRDaR8_c2LBpF_OYvwijOok7ae96N ► ? Support me on cash app: https://cash.app/$medicosis/ ► Support me on Stripe: https://donate.stripe.com/3cs02Hb9ca2k4c8fYZ ► ? Support me on Patreon: https://www.patreon.com/medicosis/ ► Support me on Venmo: Venmo: https://venmo.com/medicosis ► ? Support me on PayPal: https://www.paypal.me/perfectionalis/ ► ☕️ Buy me a Coffee: https://www.buymeacoffee.com/medicosis/ ► ? Join my Channel on YouTube: https://www.youtube.com/channel/UCl-J-ovSJhA3or73Q2uVpow/join --If you’ve joined my channel on youtube (the join button that's next to the subscribe button), then go to the "membership tab" and you will find some member-only posts/videos. ► ?‍? All of my premium courses are ON SALE: https://www.medicosisperfectionalis.com/ ? Recommended Books: https://www.amazon.com/shop/medicosisperfectionalis/ ► ❓If you have any questions, please email me at: medicosisperfectionalis@gmail.com ? Complete the Survey: https://airtable.com/shrYWjvabooT7DrcG/ ►Website: https://www.medicosisperfectionalis.com/ ►Patreon: https://www.patreon.com/medicosis/ ►YouTube: https://www.youtube.com/c/MedicosisPerfectionalis or: ► Like my page on Facebook https://www.facebook.com/medicosis/ ►Follow us on Instagram here: https://www.instagram.com/medicosisperfectionalis/ ►PayPal: https://www.paypal.me/perfectionalis/ ►Venmo: @medicosis ►Facebook: https://www.facebook.com/medicosis/ ►Twitter: https://www.twitter.com/medicosis/ ►SoundCloud: https://soundcloud.com/medicosis/ ►TikTok: www.tiktok.com/@medicosisp/ ►LinkedIn: linkedin.com/in/medicosis-perfectionalis-873886197/ ►Snapchat: https://www.snapchat.com/add/medicosis/ ►Pinterest: https://www.pinterest.com/medicosisperfectionalis/ ►Rumble: https://rumble.com/user/MedicosisPerfectionalis/ ► Tumblr: https://medicosis.tumblr.com/ Thank you so much for supporting my channel! Love ❤️& Happy studying!! ??Animated Mnemonics (Picmonic): https://www.picmonic.com/viphookup/medicosis/ ?Save on your mobile phone bill: http://fbuy.me/q6bMj ? My favorite Productivity App: https://airtable.com/invite/r/2zH40fus/ ?‍♀️ Qbank (TrueLearn): https://truelearn.referralrock.com/l/MEDICOSIS/ ? Support the channel: https://donate.stripe.com/3cs02Hb9ca2k4c8fYZ ... https://www.youtube.com/watch?v=E8Gr9xHz2lU