Jigsaw and his apprentice Amanda are dead. Now, upon the news of Detective Kerry's murder, two seasoned FBI profilers, Agent Strahm and Agent Perez, arrive in the terrified community to assist the veteran Detective Hoffman in sifting through Jigsaw's latest grisly remains and piecing together the puzzle.

As a deadly battle rages over Jigsaw's brutal legacy, a group of Jigsaw survivors gathers to seek the support of self-help guru and fellow survivor Bobby Dagen, a man whose own dark secrets unleash a new wave of terror. After trying to kill Mark Hoffman, Jill Tuck goes into protective custody. Detective Matt Gibson agrees to take her into protective custody once she signs an affidavit, revealing that Mark Hoffman is the new Jigsaw Killer. Meanwhile, Bobby Dagen, a self-proclaimed Jigsaw Survivor, is put through his own series of tests, where he must save both his friends and his wife.

Working in the shadow of his father, Detective Ezekiel "Zeke" Banks and his rookie partner take charge of an investigation into grisly murders that are eerily reminiscent of the city's gruesome past. Unwittingly entrapped in a deepening mystery, Zeke finds himself at the center of the killer's morbid game.

The victims, who survive the attack of the dangerous killer Freddy Krueger, learn to control their dreams in an attempt to fight back.