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Hypercholesterolemia Management starts with lifestyle modifications, and then lipid-lowering agents.
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Gout is a crystalline inflammatory monoarthritis arthritis that affects the first metatarsophalangeal joint (big toe, or 1st MTP).
Pseudogout is a crystalline inflammatory mono-oligo-or-poluarthritis arthritis that affects the knee, wrist, elbow, ankle, and 2nd or 3rd MTP joints.
Gout is deposition of monosodium urate (MSU) crystals.
Pseudogout is deposition of calcium pyrophosphate dihydrate (CPPD) crystals.
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Nicotinic vs Muscarinic Receptors.
Acetylcholine vs Nor-Epinephrine.
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►???Antibiotics Lectures: https://www.medicosisperfectionalis.com/products/courses/antibiotics/ ... Check out my brand new "Electrolytes" course at https://www.medicosisperfectionalis.com/products/course/electrolytes/ and use the PROMO code: ELECTROLYTES50 to get a 50% discount. ► Right Now! You can get access to all my hand-written hematology video notes (the notes that I use on my videos) on Patreon...There is a direct link through which you can view, download, print and enjoy! Go to https://www.patreon.com/medicosis (Disclaimer: The medical information contained herein is intended for educational purposes only, and are not intended for diagnosis of any illness. If you think you may be suffering from any medical condition, you should talk to your doctor or seek immediate medical attention.) If you like my videos, please consider leaving a tip at https://www.paypal.me/perfectionalis/
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Hematological malignancies can be divided into leukemias, lymphomas, and multiple myeloma.
Lymphomas can be divided into Hodgkin's lymphoma and non-Hodgkin's lymphoma.
Non-Hodgkin's lymphoma can be subdivided into aggressive lymphoma and indolent lymphoma.
Aggressive non-Hodgkin's lymphomas include:
*Diffuse large B-cell lymphoma (DLBCL)
*Burkitt's lymphoma.
*Mantle cell lymphoma.
*Precursor T-cell lymphoblastic lymphoma.
*B-lymphoblastic lymphoma.
Indolent non-Hodgkin's lymphomas include:
*Follicular lymphoma
*Marginal zone B-cell lymphoma (MALToma)
*Hairy cell leukemia/ lymphoma.
*Waldenstrom macroglobulinemia.
*Mycosis fungoides/ Sezary syndrome.
Diffuse Large B-cell lymphoma (DLBCL) is an aggressive Non-Hodgkin's lymphoma (NHL)...It's the most common NHL.
To diagnose, you need a core needle biopsy or an excisional biopsy of the lymph node
Uric acid levels can be high---Give allopurinol (Xanthine oxidase inhibitor).
Staging of cancer is important (Ann-Arbor classification based on history, physical exam and CT scan)
Treatment: Combination Chemotherapy (R-CHOP) regimen.
Tumor lysis syndrome can ensue.
PET scan is helpful.
The lymph node is a bean-shaped body (not a gland) that interrupts the flow of lymph through the lymphatic vessels.
Afferent lymphatics go towards the lymph node, while efferent exits the node. The lymph node has cortex (which contains the follicle, germinal center, mantle, and margin).
Lymphocyte activation and differentiation occur in the lymph node.
Lymph is a colorless fluid that floats in the lymphatic vessels (lymphatics) of your lymphatic systems.
Formed from the interstitial fluid (extracellular fluid) and returns back to the big veins (Superior vena cava) through the thoracic duct and Right lymphatic duct.
Lymph slows down when it passes in lymph nodes.
Lacteals are a special type of lymph, they are milky because they contain chylomicrons.
Lymph node enlargement can happen in cases of lymphoma (painless lymphadenopathy) or infection (painful).
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