New nanoparticles can perform gene editing in the lungs
Engineers at MIT and the University of Massachusetts Medical School have designed a new type of nanoparticle that can be administered to the lungs, where it can deliver messenger RNA encoding useful proteins.
With further development, these particles could offer an inhalable treatment for cystic fibrosis and other diseases of the lung, the researchers say.
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Henry Ford (July 30, 1863 -- April 7, 1947) was an American industrialist, the founder of the Ford Motor Company, and sponsor of the development of the assembly line technique of mass production.
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In recent years, engineers have found ways to modify the properties of some “two- dimensional” materials, which are just one or a few atoms thick, by stacking two layers together and rotating one slightly in relation to the other. This creates what are known as moiré patterns, where tiny shifts in the alignment of atoms between the two sheets create larger-scale patterns. It also changes the way electrons move through the material, in potentially useful ways.
But for practical applications, such two-dimensional materials must at some point connect with the ordinary world of 3D materials. An international team led by MIT researchers has now come up with a way of imaging what goes on at these interfaces, down to the level of individual atoms, and of correlating the moiré patterns at the 2D-3D boundary with the resulting changes in the material’s properties.
The new findings are described in the journal Nature Communications.
Research paper: Direct imaging and electronic structure modulation of moiré superlattices at the 2D/3D interface https://www.nature.com/articles/s41467-021-21363-5
News Source: https://news.mit.edu/2021/2d-3d-materials-electronic-microscope-0226
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The Kidney Project’s implantable bioartificial kidney, one that promises to free kidney disease patients from dialysis machines and transplant waiting lists, took another big step toward becoming reality, earning a $650,000 prize from KidneyX for its first-ever demonstration of a functional prototype of its implantable artificial kidney.
News Source: https://pharmacy.ucsf.edu/news/2021/09/kidney-project-successfully-tests-prototype-bioartificial-kidney
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Solid-state inorganic materials are critical to the growth and development of electric vehicle, cell phone, laptop battery and solar energy technologies. However, finding the ideal materials with the desired functions for these industries is extremely challenging.
Due to the vast chemical design space and the high sparsity of candidates, experimental trials and first-principle computational simulations cannot be used as screening tools to solve this problem. Instead, researchers have developed a deep learning-based smart algorithm that uses a technique called generative adversarial network (GAN) model to dramatically improve the material search efficiency up to two orders of magnitude. It has the potential to greatly speed up the discovery of novel functional materials.
The work, published in the journal Nature NPJ Computational Materials was a collaboration between researchers at the University of South Carolina College of Engineering and Computing and Guizhou University, a research university located in Guiyang, China.
Research Paper: Generative adversarial networks (GAN) based efficient sampling of chemical composition space for inverse design of inorganic materials https://www.nature.com/articles/s41524-020-00352-0
News Source: https://www.sc.edu/study/colleges_schools/engineering_and_computing/news_events/news/2020/hu_materialsdiscovery_ai.php
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A Cleveland Clinic study shows that among patients with obesity, prior weight loss achieved with bariatric surgery was associated with a 60% lower risk of developing severe complications from COVID-19 infection. The research was published in the journal JAMA Surgery.
Research paper: Association of Weight Loss Achieved Through Metabolic Surgery With Risk and Severity of COVID-19 Infection https://jamanetwork.com/journals/jamasurgery/fullarticle/2787613
News source: https://newsroom.clevelandclinic.org/2021/12/29/substantial-weight-loss-can-reduce-risk-of-severe-covid-19-complications/
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A water battery capable of storing electricity equivalent to 400,000 electric car batteries will begin operating in Switzerland.
With the ability to store and generate vast quantities of hydroelectric energy, the battery will play an important role in stabilising power supplies in Switzerland and Europe.
A water battery or pumped storage power plant is a type of hydroelectric energy storage. The battery is made from two large pools of water located at different heights.
Credit: Nant de Drance
News Source: https://www.euronews.com/green/2022/06/30/enormous-water-battery-in-switzerland-will-help-prevent-power-shortages
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Recently many people are getting interested to know about AI Tools like OpenAI Playground. Because recently a Reddit post about it became viral. In that post, a student was saying that he uses OpenAI's playground tool for completing school homework, like writing essays.
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Using new materials that emits a narrow electron probe, researchers have developed an ultrafast electron beam technique to probe small, thin pieces of quantum materials with very high resolution.
Credit: Cornell University
Research Paper: A kiloelectron-volt ultrafast electron micro-diffraction apparatus using low emittance semiconductor photocathode https://www.osti.gov/biblio/1868951
News Source: https://www.eurekalert.org/news-releases/1001027
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