Æon Flux is set in a surreal German Expressionist style futuristic universe. The setting comprises a bizarre post-apocalyptic dystopian world surrounded by endless barren wasteland, mutant creatures, clones, and robots within the last two separated border wall cities of Monica and Bregna similar to the Berlin Wall, located somewhere in former Eastern Europe after an environmental catastrophe that wiped out 99 percent of the global population. The title character is a tall, sexy, dominatrix scantily-clad secret agent from the city of Monica, skilled in espionage, assassination and acrobatics. Her mission is to infiltrate and destroy the strongholds of the city of Bregna /ˈbrɛnjə/, which is led by her sworn enemy, and sometimes lover, Trevor Goodchild, the technocratic dictator of Bregna, whose citizens are called Breens. The two cities engage in a futile never ending war for ideological supremacy; while Monica represents a dynamic nihilistic anarchist society where rules do not exist, Bregna embodies a centralized scientific planned Orwellian police state. The names of their respective characters reflect this: Flux as the self-directed agent from Monica and Goodchild as the self-appointed leader of Bregna. The term Æon comes from the Gnostic notion of Æons as emanations of the God, who come in male/female pairs (here Flux and Goodchild). This juxtaposition also maps accordingly to the characterizations of Eris and Greyface in the Discordian mythos. Further mythic parallels can be drawn in likening Goodchild to Apollo and Flux to Artemis.

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Æon Flux is set in a surreal German Expressionist style futuristic universe. The setting comprises a bizarre post-apocalyptic dystopian world surrounded by endless barren wasteland, mutant creatures, clones, and robots within the last two separated border wall cities of Monica and Bregna similar to the Berlin Wall, located somewhere in former Eastern Europe after an environmental catastrophe that wiped out 99 percent of the global population. The title character is a tall, sexy, dominatrix scantily-clad secret agent from the city of Monica, skilled in espionage, assassination and acrobatics. Her mission is to infiltrate and destroy the strongholds of the city of Bregna /ˈbrɛnjə/, which is led by her sworn enemy, and sometimes lover, Trevor Goodchild, the technocratic dictator of Bregna, whose citizens are called Breens. The two cities engage in a futile never ending war for ideological supremacy; while Monica represents a dynamic nihilistic anarchist society where rules do not exist, Bregna embodies a centralized scientific planned Orwellian police state. The names of their respective characters reflect this: Flux as the self-directed agent from Monica and Goodchild as the self-appointed leader of Bregna. The term Æon comes from the Gnostic notion of Æons as emanations of the God, who come in male/female pairs (here Flux and Goodchild). This juxtaposition also maps accordingly to the characterizations of Eris and Greyface in the Discordian mythos. Further mythic parallels can be drawn in likening Goodchild to Apollo and Flux to Artemis.