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66952
Author: Helen L. Henry
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The Encyclopedia of Hormones is a comprehensive reference work on hormones in vertebrate, invertebrate, and plant systems. It covers all aspects of hormones their chemical structure and biological synthesis the major physiological systems in which they operate the cellular and subcellular site of their action the nature of the signal transduction mechanisms used in the hormones action and the biological consequences of an excess or deficiency of the hormone. Each contributor is an expert in his or her field and has been recruited by one of 14 Associate Editors. The 300 articles that comprise this encyclopedia are arranged alphabetically. Each entry begins with a glossary of key terms that are compiled into a complete glossary for the entire work. Additionally, each entry includes 10-15 recent references to provide the reader with an entry into the scientific literature. The Encyclopedia of Hormones is sure to be a valuable reference work for students and professional researchers interested in any aspect of the control of biological systems by hormonal signals. ullThe only source available with such comprehensive descriptions of hormones, their receptors, and their mechanisms of action llFull coverage including vertebrate, invertebrate, and plant hormones llIncludes the chemistry, synthesis, secretion, and biological actions of hormones llThorough coverage of signal transduction mechanisms as they relate to hormones llContributions from over 500 experts in the study of hormones llWritten to be accesssible to non-endocrinologistslulReviewThe preface carefully defines hormone, where the editors explain they have expanded the classic meaning of chemical messenger to include local paracrine and autocrine signals...Highly recommended. -CHOICE, 2003...an important addition to the reference collections of biology and health science libraries.a valuable reference source and highly recommended for medical libraries as well as other life science collections.E-STREAMS (April 2004)This three-volume encyclopedia is the first of its kind. It covers the vast field of molecular endocrinology in 296 articles from over 500 contributors who were recruited and invited to write by 14 associate editors, all of whom were specifically chosen by executive editors Helen Henry and Anthony Norman...It is evident that great care went into the compilation of this professional, multi-volume resource...The Encyclopedia of Hormones is highly recommended for academic science and medical school libraries. -AMERICAN REFERENCE BOOKS (2004)Highly Recommended -CHOICE (December 2003) About the AuthorHelen L. Henry received her Ph.D. in 1970 from Washington University, St. Louis and did postdoctoral work in animal reproduction at Ohio State University. Following further postdoctoral work at University of California, Riverside, she joined the faculty and is currently Professor of Biochemistry. From 1990 to 1996 she served as Associate Dean of Biological Sciences in the College of Natural and Agricultural Sciences.Dr. Henrys laboratory has made major contributions to the understanding of vitamin D metabolism, particularly regulation of the production of the active vitamin D hormone by the kidney. She pioneered the use of cell culture systems to study renal vitamin D metabolism. A related area of research focus is the regulation of gene expression in the kidney by 1,25-dihydroxyvitamin D3. In addition to peer-reviewed research articles, Dr. Henry has authored chapters for the books Vitamin D and Handbook of Physiology, as well as the chapter on Vitamin D Metabolism for this Encyclopedia.Dr. Henry was awarded a National Institutes of Health (NIH) Research Career Development Award in 1977. She received the Fuller Albright Award from the American Society for Bone and Mineral Research in 1984 and has served this Society as a member of the Council and several Scientific Program Committees. Dr. Henry has been a member of the NIH General Medicine B Study Section (1989-1993) and the National Science Foundation Panel on Integrative Biology (1994-1996). She has served on the editorial boards of several scientific journals, including Endocrinology, American Journal of Physiology, and the Journal of Bone and Mineral Research. She is currently a member of the Endocrine Society, the American Society of Biochemistry and Molecular Biology, the American Society for Bone and Mineral Research, and the American Institute of Nutritional Sciences.Anthony W. Norman received his A.B. from Oberlin College in 1959, and an M.S. and Ph.D. in Biochemistry in 1961 and 1963, respectively, from the University of Wisconsin, Madison. Following postdoctoral work in Paul D. Boyers group at UCLA, in 1964 he joined the Department of Biochemistry at University of California, Riverside, as an Assistant Professor. From 1976 to 1981 he served as Chair of the department and currently holds a Presidential Chair and is a Distinguished Professor of Biochemistry and Biomedical Sciences. Dr. Norman has also been active for some 25 years in medical education on the UC-Riverside campus and at UCLA through participation in the URUCLA Program in Biomedical Sciences, of which he was Dean and Director from 1986 to 1991.Dr. Normans biomedical research career has focused on the mechanism of action of the vitamin D family of steroids. His chief contributions to these areas of cellular and molecular endocrinology have played a pivotal role in defining the boundaries of this research domain via discoveries that have opened new areas of investigation. The first of these was the discovery in 1968, and chemical characterization in 1971, of the hormonally active form of vitamin D, 1a,25(OH)2-vitamin D3. Subsequent achievements include the discovery and characterization of the nuclear receptor for 1a,25(OH)2D3, the clinical evaluation of 1a,25(OH)2D3 in renal osteodystrophy, articulation of the concept of the vitamin D endocrine system, the importance of 1a,25(OH)2D3 to insulin secretion and the discovery of a new rapid, nongenomic, signal transduction process for 1a,25(OH)2D3. Dr. Norman has been the recipient of awards that include a Fulbright Fellowship, 1970 Public Health Service Career Development Award, 1970 Mead Johnson Award, American Institute of Nutrition, 1977 Ernst Oppenheimer Award, Endocrine Society, 1977 Visiting Lecturer Australian Society of Endocrinology, 1978 Visiting Faculty Member, Mayo Clinic, 1981 Prix Andre
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23871
Author: Adam Bradley
File Type: epub
Ralph Ellison may be the preeminent African-American author of the twentieth century, though he published only one novel, 1952s Invisible Man. He enjoyed a highly successful career in American letters, publishing two collections of essays, teaching at several colleges and universities, and writing dozens of pieces for newspapers and magazines, yet Ellison never published the second novel he had been composing for more than forty years. A 1967 fire that destroyed some of his work accounts for only a small part of the novels fate the rest is revealed in the thousands of pages he left behind after his death in 1994, many of them collected for the first time in the recently published Three Days Before the Shooting . . . .Ralph Ellison in Progress is the first book to survey the expansive geography of Ellisons unfinished novel while re-imaging the more familiar, but often misunderstood, territory of Invisible Man. It works from the premise that understanding Ellisons process of composition imparts important truths not only about the author himself but about race, writing, and American identity. Drawing on thousands of pages of Ellisons journals, typescripts, computer drafts, and handwritten notes, many never before studied, Adam Bradley argues for a shift in scholarly emphasis that moves a greater share of the weight of Ellisons literary legacy to the last forty years of his life and to the novel he left forever in progress.**From BooklistStarred Review Bradley, a coeditor of Ellisons unfinished novel, Three Days before the Shooting, plumbs the long and arduous process Ellison employed in writing the highly acclaimed Invisible Man and his failure to complete his second novel. Bradley begins in the 1990s with Ellisons efforts to finish his second novel and moves backward through a promising career that saw huge changes in American racial politics and publishing. Ellison, who died in 1994, was one of the first major American writers to go digital, switching to a computer in 1982. Bradley argues that the move, rather than improving Ellisons productivity, only created more opportunities for revisions for an obsessive perfectionist. Sifting through 27 boxes of archival material, Bradley found evidence that Ellisons delays were less about psychological blocks (a 1967 fire destroyed much of his work) than artistic angst. Bradley compares the creation of both novels and Ellisons choices of plot and character development, reflecting Ellisons own struggles to come to terms with racial identity and individualism. This book adds enormously to the great pastime of analyzing why Ellison never finished his second novel and why he remains an acclaimed and enduring figure in American literature. --Vanessa Bush Review[Bradley] argues that the work Ellison did in the second half of his life reveals even more about the writers artistic agenda and ambition than Invisible Man doesand allows us to read that classic work with fresh eyes. Jennifer Howard, *Chronicle of Higher Education * (Jennifer Howard Chronicle of Higher Education) Bradleys work projects new possibilities in Ellison scholarship in the context of the digital age. Whether, warts and all, unfinished as it is, Ellisons second novel is the 21st centurys first candidate for the Great American Novel, as Bradley asserts, will be hotly debated. There is plenty in Ralph Ellison in Progress to facilitate that debate.Steven C. Tracy, The Review of English Studies(Steven C. Tracy The Review of English Studies) Ralph Ellison in Progress will quickly stand as the most important book on Ellison as a working writer, both for the case it makes in explanation of his notorious inability to finish his second novel and for tracing the long arc of his career from Invisible Man through the fascinating mass of manuscript materials posthumously published under the title Three Days Before the Shooting.Eric Sundquist, author of Kings Dream (Eric Sundquist) Adam Bradleys brilliant work of literary archaeology delivers revelations that illuminate Ralph Ellisons life, philosophy, and fiction. If you have not read Ralph Ellison in Progress, you cannot say you understand the genius that guided this giant of American literature.Dr. Charles Johnson, author of Middle Passage (Dr. Charles Johnson) Perhaps the most discussed book in American literature is one that remained incomplete. Did Ralph Ellisons second novel remain unfinished because he used WordStar? Or did he keep writing the same passages over and over again like Jack Nicholson in The Shining? Like a literary detective, Adam Bradley explores all of the theories about what prevented Ellison from writing a follow up to Invisible Man. Another thing Adam Bradley has made literary criticism interesting again.Ishmael Reed, author of Barack Obama and the Jim Crow Media (Ishmael Reed) Armed with unparalleled access to, and knowledge of, Ellisons manuscripts, Adam Bradley delivers a major achievement. Ralph Ellison in Progress really is groundbreaking scholarship there is nothing quite like it.James A. Miller, author of Remembering Scottsboro The Legacy of an Infamous Trial (James A. Miller) An original and groundbreaking argument that willthis is no mere hyperboletransfigure Ellison scholarship and criticism as we know it.David Yaffe, author of Fascinating Rhythm Reading Jazz in American Writing (David Yaffe)
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