Our Website: https://www.findinggeniuspodcast.com/ Subscribe and review our Podcast on iTunes: https://apple.co/2L6tN88 Follow us on: Facebook: https://web.facebook.com/futuretechpodcast/ Twitter: https://twitter.com/finding_genius Instagram: https://www.instagram.com/findinggeniuspodcast/ LinkedIn: https://www.linkedin.com/company/finding-genius-podcast/ How can GI health significantly determine the general health of the rest of the body? Since so many bodily systems utilize products produced along the gastrointestinal tract, minor issues can be increased throughout the body. Listen up to learn: 1. How the gut microbiome has the potential to make or break the body's health 2. How the Western diet may be threatening your gut's health 3. How "bacterial economics" governs GI systems Executive vice president and chief medical officer at Seres Therapeutics, Dr. Lisa von Moltke, discusses her work developing therapeutic techniques to treat gastrointestinal conditions and microbiomes. Through the study of how the gut microbiome and gastrointestinal health affect the operation of the rest of the body, new therapies have been developed to combat GI-targeted infections. New therapies are also being produced to prevent infection with patients undergoing transplants and grafts. Immunosuppressants are also a weak point regarding gut health since they open windows of vulnerability for infections to target your gut. Therefore, developing techniques to treat various diseases without affecting GI health and the gut microbiome may be the next most valuable step in developing pharmaceutical therapeutics. For more information, visit serestherapeutics.com. Episode also available on Apple Podcasts: apple.co/30PvU9C #therapeuticdevelopment #microbiometherapeutics #FindingGeniusPodcast ... https://www.youtube.com/watch?v=nXZY0GlNwbA

Our Website: https://www.findinggeniuspodcast.com/ Subscribe and review our Podcast on iTunes: https://apple.co/2L6tN88 Follow us on: Facebook: https://web.facebook.com/futuretechpodcast/ Twitter: https://twitter.com/finding_genius Instagram: https://www.instagram.com/findinggeniuspodcast A Tyrannosaurus rex prompted a successful radiologist of over 30 years to redirect his focus on something completely different: evolutionary biology. Press play for a fascinating look into the mind of William B. Miller, Jr., where medicine, evolution, and virology intersect. Press play to explore: Are viruses alive, and if so, does that mean they’re self-aware? Are viruses capable of contingent decision-making, and if so, how should that direct the means by which we control them for our own benefit? In what way living things “know” doubt and make predictions, and what this may imply about viruses As a radiologist, Dr. Miller noticed recurring patterns of overlap between infectious diseases and cancer. At the time, scientific evidence provided Dr. Miller with no explanation as to why he was noticing these reiterative patterns. Then he met Sue, one of the world’s best-preserved Tyrannosaurus rex specimens. He noticed several features of the skeleton that were shared by the human skeleton, and his interest was piqued like never before. He dove into a new understanding of evolution of life on earth: evolution based on cognition. Rather than subvert Darwinism, it explains it in an arguably better way, and according to Dr. Miller, leads directly to the question of how to place viruses in the correct evolutionary schema. This conversation leads to so many compelling topics, including how infectious disease and evolution mirror each other, the concept of the virocell, forms of communication between viruses, a new science called sociovirology which involves the ideas of cooperation, codependence, and collaboration between viruses, why a virus is either lytic, lysogenic, or endogenizing, philosophical implications of the virome, what Dr. Miller means when he refers to viral “personalities,” in what way the principle of parsimony seems violated by the sheer number of incomplete virions in certain viral infections, how the idea of quasi-species has been used as one of the origin of life theories, where he believes the field of virology needs to go, and so much more. Check out Dr. Miller’s book, The Microcosm Within: Evolution and Extinction in the Hologenome, and visit his website at http://www.themicrocosmwithin.com/. Available on Apple Podcasts: apple.co/2Os0myK #viruses #humanvirome #Findinggeniuspodcast #biology #science #virus #health #evoloution #nature #Healthpodcast #InternalMedicinepodcast #Biosciencespodcast ... https://www.youtube.com/watch?v=b3-Ss8rAGH0

Our Website: https://www.findinggeniuspodcast.com/ Subscribe and review our Podcast on iTunes: https://apple.co/2L6tN88 Follow us on: Facebook: https://web.facebook.com/futuretechpodcast/ Twitter: https://twitter.com/finding_genius Instagram: https://www.instagram.com/findinggeniuspodcast/ LinkedIn: https://www.linkedin.com/company/finding-genius-podcast/ "This is the worse superbug you can get," said her husband's doctors when diagnosing him with a life-threatening multidrug resistant bacterial infection.  But Steffanie Strathdee put her research skills to work and eventually was able to convince doctors to treat him with an experimental phage therapy that ended up saving his life. Listen and learn 1. Why no other solution was working to cure her husband of this superbug, 2. How the history of phage therapy versus antibiotics has played out, and 3. Why the problem of antibiotic resistance may be addressed by utilizing bacteriophages. Steffanie A. Strathdee is the Associate Dean of Global Health Sciences and the Harold Simon Professor in the Department of Medicine at the University of California San Diego School of Medicine. She helped found and co-directs UCSD’s new center for Innovative Phage Applications and Therapeutics (IPATH) and also works with the Global Health Institute and the International Core of UCSD’s Center for AIDS Research. An infectious disease epidemiologist, she's also the author of The Perfect Predator, which tells the story of her husband's struggle with a superbug and the successful effort to help him recover with phage viruses. Phages are viruses that infect bacteria, and are emerging as a potential winner as scientists struggle with how to prevent superbugs from causing deadly infections.  She gives listeners a fascinating history of how politics and war kept phage therapy out of American medicine for decades. First discovered by a French Canadian microbiologist, their adoption by Russians pre-World War II marked them as off-the-table for the American medical field. But they are emerging again as having great potential, and Steffanie Strathdee helps enlighten listeners by describing the process and why they can be effective. First, scientists are able to pick and choose their phages, testing to make sure what bacteria the phages will infect. They can get specific, killing only the bacteria they want to target. Ideally, they'll collect a couple of different phages for the best chances of success, then make isolates of them.  The most difficult stage is the purification, she says. Scientists are moving ahead, designing clinical studies. Listen in for more exciting news about this life-saving treatment. For more, see the Innovative Phage Applications and Therapeutics (IPATH) website. Available on Apple Podca ... https://www.youtube.com/watch?v=WTXFTaHjbsc

Our Website: https://www.findinggeniuspodcast.com/ Subscribe and review our Podcast on iTunes: https://apple.co/2L6tN88 Follow us on: Facebook: https://web.facebook.com/futuretechpodcast/ Twitter: https://twitter.com/finding_genius Instagram: https://www.instagram.com/findinggeniuspodcast/ Dr. Schilsky is a professor of medicine and surgery and medical director of liver transplantation at Yale, and he joins the show today to discuss issues related to the liver and liver transplantation. Tune in to learn the following: 1. Under what conditions the use of acetaminophen can become a problem for liver and overall health 2. In what ways and to what extent the liver is regenerative 3. The relationship between atherosclerosis (which leads to a higher risk of heart attack and stroke) and fatty liver disease Dr. Schilsky had the privilege of witnessing the transition of organ transplantation from the imaginary world, to the world of practical application, to the world of successful application. He has seen firsthand the influence of pharmacology and advanced techniques on the outcomes in this field, and perhaps most importantly, increased quality of life and lifespan enjoyed by patients. For Dr. Schilsky, this is precisely where his interests exist: in the space where patient care and science marry. He discusses acute and chronic injuries to the liver, the safeness of acetaminophen, infectious causes of liver diseases, the crucial balance between liver injury and regeneration, the relationship between NSAIDs and kidney malfunction and other disorders, non-alcoholic fatty liver disease, when and why life-saving bariatric surgeries may be performed, the absence of signs in early stages of liver diseases, whether or not liver diseases tend to happen in certain locations of the liver, and so much more. Learn more at https://liverfoundation.org/ and https://www.niddk.nih.gov/health-information/liver-disease. #Findinggeniuspodcast #Surgery #LiverTransplant #Healthpodcast #Medicinepodcast #Biosciencespodcast ... https://www.youtube.com/watch?v=PJbV32xRVDc