The whole gang are back and as close as ever. They decide to get even closer by spending the summer together at a beach house. They decide to hold the biggest party ever to be seen, even if the preparation doesn't always go to plan. Especially when Stifler, Finch and Jim become more close to each other than they ever want to be and when Jim mistakes super glue for lubricant.

When New Orleans Police Detective Danny Fisher stops a brilliant thief from getting away with a multimillion-dollar heist, the thief's girlfriend is accidentally killed. After escaping from prison, the criminal mastermind enacts his revenge, taunting Danny with 12 rounds of near-impossible puzzles and tasks that he must somehow complete to save the life of the woman he loves.

Given the country's overcrowded prisons, the U.S. government begins to allow 12-hour periods of time in which all illegal activity is legal. During one of these free-for-alls, a family must protect themselves from a home invasion.

While the original parodied slasher flicks like Scream, Keenen Ivory Wayans's sequel to Scary Movie takes comedic aim at haunted house movies. A group of students visit a mansion called "Hell House," and murderous high jinks ensue.