Today we will be covering the results of my Spinal Tap. Below I’ve included the articles referenced in the video as well as my CSF findings. Abnormal findings indicated by ( ! ) prefix. Brain Barriers and brain fluids research in 2020...: https://fluidsbarrierscns.biomedcentral.com/articles/10.1186/s12987-021-00258-z Next-Generation Sequencing of Cerebrospinal Fluid...: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6018529/ Clinical associations of anti-Smith antibodies in PROFILE: a multi-ethnic lupus cohort: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4475431/ IgG levels in cerebrospinal fluid of patients with central nervous system manifestations of systemic lupus erythematosus: https://www.sciencedirect.com/science/article/abs/pii/0090122972900025 ( ! ) CELL COUNT DIFF, CSF CELL COUNT, CSF[334432030] Final result ( ! ) DIFFERENTIAL, CSF[336854000] Abnormal Final result CULT, CSF BACTI Culture Report: No growth GRAM SMEAR ONLY, STAT GRAM STAIN RESULT No organisms seen No organisms seen SMEAR PREPARATION Cytospin SOURCE BODY SITE CSF GLUCOSE, CSF Component Your Value Standard Range GLUCOSE CSF 54 mg/dL 40 - 70 mg/dL HSV QUALITATIVE PCR, CSF Component Your Value Standard Range HSV-1 QUALITATIVE PCR, CSF Undetected - HSV-2 QUALITATIVE PCR, CSF Undetected - CRYPTOCOCCAL ANTIGEN- CSF Component Your Value Standard Range CRYPTO AG, CSF Negative Negative PROTEIN, CSF Component Your Value Standard Range TOTAL PROTEIN CSF 29 mg/dL 15 - 45 mg/dL VDRL CSF Component Your Value Standard Range VDRL Non Reactive Non Reactive LYME ABS TOTAL ELISA, CSF Component Your Value Standard Range LYME AB ELISA, CSF 0.03 LIV less than 0.99 LIV ENCEPHALOPATHY AUTOIMMUNE/PARANEOPLASTIC EVAL, CSF ENCEPHALOPATHY INTERPRETATION, CSF SEE COMMENTS No informative autoantibodies were detected in this evaluation. However, a negative result does not exclude autoimmune encephalopathy, idiopathic or paraneoplastic. Sensitivity and specificity of antibody testing are enhanced by testing both serum and CSF. AMPA-R AB CBA, CSF Negative Negative AMPHIPHYSIN AB, CSF Negative titer 1:2 titer AGNA-1, CSF Negative titer \/1:2 titer ANNA-1, CSF Negative titer \/1:2 titer ANNA-2, CSF Negative titer \/1:2 titer ANNA-3, CSF Negative titer \/1:2 titer CASPR2-IGG CBA, CSF Negative Negative CRMP-5-IGG, CSF Negative titer \/1:2 titer DPPX AB IFA, CSF Negative Negative GABA-B-R AB CBA. CSF Negative Negative GAD65 AB ASSAY, CSF 0.00 nmol/L \/ or equal to 0.02 nmol/L GFAP IFA, CSF Negative Negative IGLON5 IFA, CSF Negative Negative LGI1-IGG CBA, CSF Negative Negative MGLUR1 AB IFA, CSF Negative Negative NIF IFA, CSF Negative Negative NMDA-R AB CBA, CSF Negative Negative PCA-1, CSF Negative titer \/1:2 titer PCA-2, CSF Negative titer \/1:2 titer PCA-TR,CSF Negative titer \/1:2 titer CELL COUNT, CSF Component Your Value Standard Range CSF APPEARANCE Clear Clear CSF COLOR Colorless Colorless CSF TUBE NUMBER #4 CSF WBC 1 /cu mm 0 - 5 /cu mm CSF RBC \/1 /cu mm \/1 /cu mm TOXOPLASMA IGG AB, CSF Component Your Value Standard Range TOXOPLASMA IGG, CSF \/0.90 REFERENCE RANGE: \/0.90 ENTEROVIRUS BY PCR, CSF ONLY Component Your Value Standard Range ENTEROVIRUS PCR FOR CSF ONLY Negative Negative CMV PCR Qual Component Your Value Standard Range Flag CMV PCR QUALITATIVE Not Detected ( ! ) DIFFERENTIAL, CSF Component Your Value Standard Range Flag NEUTROPHIL (CSF) 0 % 0 - 6 % ( ! ) LYMPHOCYTES(CSF) 88 % 40 - 80 % H ( ! ) MONOCYTES(CSF) 12 % 15 - 45 % L MACROPHAGES(CSF) 0 % % EOSINOPHILS(CSF) 0 % % BASOPHILS(CSF) 0 % % LINING CELLS 0 % % REACTIVE LYMPHS(CSF) 0 % % ATYPICAL CELLS(CSF) 0 % 0.0 % TOTAL CELL COUNTED,CSF 43 ( ! ) OLIGOCLONAL BNDS/IGG SYN RATE Component Your Value Standard Range Flag OLIGOCLONAL BANDS SF Negative Negative ALBUMIN, SERUM-OLI 4500 mg/dL 3500 - 5200 mg/dL ALBUMIN, CSF 16 mg/dL 0 - 35 mg/dL ALBUMIN INDEX-OLI 3.6 ratio 0.0 - 9.0 ratio IGG INDEX 0.62 ratio 0.28 - 0.66 ratio CSF/IGG ALBUMIN RATIO 0.10 ratio 0.09 - 0.25 ratio IGG SYN RATE \/0.0 mg/d \/ or equal to 8.0 mg/d CSF OLIGOCLONAL BANDS NUMBER 0 Bands 0 - 1 Bands OLIGOCLONAL COMMENTS See Note Isoelectric focusing/immunofixation revealed no oligoclonal bands in either the CSF or the serum. This is considered to be a negative result for oligoclonal bands. Approximately 5 percent of patients with clinically definitive multiple sclerosis will have a negative result. ( ! ) IGG SERUM 731 mg/dL 768 - 1632 mg/dL L REFERENCE INTERVAL: Immunoglobulin G IGG CSF 1.6 mg/dL 0.0 - 6.0 mg/dL ENCEPHALOPATHY AUTOIMMUNE/PARANEOPLASTIC EVAL, SERIUM Same results as CSF CNS DEMYELINATING DISEASE EVAL, SERUM Component Your Value Standard Range Flag CNS DEMYELINATING DISEASE INTERP, SERUM SEE COMMENTS No informative autoantibodies were detected in this evaluation. A negative result does not preclude a diagnosis of an inflammatory CNS demyelinating disorder. MOG FACS, SERUM Negative Negative NMO/AQP4-IGG Negative Negative ... https://www.youtube.com/watch?v=khoED54dzmQ